6ZP1

Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State

Summary for 6ZP1

• Entry DOI: 10.2210/pdb6zp1/pdb
• EMDB information: 11333
• Descriptor: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: coronavirus, sars-cov-2, spike protein, s protein, s antigen, covid-19, receptor binding, membrane fusion, vaccine design, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 3
• Total formula weight: 428502.36

Authors

Xiong, X.,Qu, K.,Scheres, S.H.W.,Briggs, J.A.G. (deposition date: 2020-07-08, release date: 2020-07-22, Last modification date: 2021-06-02)

• Primary citation: Xiong, X.,Qu, K.,Ciazynska, K.A.,Hosmillo, M.,Carter, A.P.,Ebrahimi, S.,Ke, Z.,Scheres, S.H.W.,Bergamaschi, L.,Grice, G.L.,Zhang, Y.,Nathan, J.A.,Baker, S.,James, L.C.,Baxendale, H.E.,Goodfellow, I.,Doffinger, R.,Briggs, J.A.G.; A thermostable, closed SARS-CoV-2 spike protein trimer.; Nat.Struct.Mol.Biol., 27:934-941, 2020; PubMed: 32737467; DOI: 10.1038/s41594-020-0478-5

Experimental method

ELECTRON MICROSCOPY (3.3 Å)