7QJW
In vitro assembled tau filaments with structures like chronic traumatic encephalopathy type II (8a)
Summary for 7QJW
| Entry DOI | 10.2210/pdb7qjw/pdb |
| EMDB information | 14024 |
| Descriptor | Microtubule-associated protein tau (1 entity in total) |
| Functional Keywords | alzheimer's disease, amyloid, tau, neurodegeneration, chronic traumatic encephalopathy, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 275519.23 |
| Authors | Lovestam, S.,Scheres, S.H.W. (deposition date: 2021-12-17, release date: 2022-01-19, Last modification date: 2022-03-16) |
| Primary citation | Lovestam, S.,Koh, F.A.,van Knippenberg, B.,Kotecha, A.,Murzin, A.G.,Goedert, M.,Scheres, S.H.W. Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy. Elife, 11:-, 2022 Cited by PubMed: 35244536DOI: 10.7554/eLife.76494 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.81 Å) |
Structure validation
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