7QJV

In vitro assembled tau filaments into Quadruple Helical Filaments type 1 (2c)

Summary for 7QJV

Entry DOI	10.2210/pdb7qjv/pdb
EMDB information	14023
Descriptor	Microtubule-associated protein tau (1 entity in total)
Functional Keywords	neurodegeneration, amyloid, tau, alzheimer's disease, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	12
Total formula weight	551038.45
Authors	Lovestam, S.,Scheres, S.H.W. (deposition date: 2021-12-17, release date: 2022-02-16, Last modification date: 2022-03-16)
Primary citation	Lovestam, S.,Koh, F.A.,van Knippenberg, B.,Kotecha, A.,Murzin, A.G.,Goedert, M.,Scheres, S.H.W. Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy. Elife, 11:-, 2022 Cited by PubMed: 35244536 DOI: 10.7554/eLife.76494 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.29 Å)

Structure validation