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PDB: 198 件

6SRS
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Structure of the Fanconi anaemia core subcomplex
分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), ...
著者Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
登録日2019-09-05
公開日2019-11-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6SRI
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Structure of the Fanconi anaemia core complex
分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), ...
著者Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
登録日2019-09-05
公開日2019-11-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6TJO
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Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-26
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
8BG9
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Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta
分子名称: Amyloid-beta protein 40
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BG0
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Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40
分子名称: Amyloid-beta precursor protein
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BFZ
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Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42
分子名称: Amyloid-beta precursor protein
著者Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordberg, A, Goedert, M, Scheres, S.H.W.
登録日2022-10-27
公開日2023-01-18
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BYN
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BU of 8byn by Molmil
Chronic traumatic encephalopathy tau filaments with PET ligand flortaucipir
分子名称: 7-(6-fluoranylpyridin-3-yl)-5~{H}-pyrido[4,3-b]indole, Microtubule-associated protein tau
著者Shi, Y, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2022-12-13
公開日2023-01-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir.
J.Mol.Biol., 435, 2023
8CAX
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Structure of Tau filaments Type II from Subacute Sclerosing Panencephalitis
分子名称: Microtubule-associated protein tau
著者Qi, C, Hasegawa, M, Takao, M, Sakai, M, Akagi, M, Iwasaki, Y, Yoshida, M, Scheres, S.H.W, Goedert, M.
登録日2023-01-24
公開日2023-11-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Acta Neuropathol Commun, 11, 2023
8CAQ
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Structure of Tau filaments Type I from Subacute Sclerosing Panencephalitis
分子名称: Microtubule-associated protein tau
著者Qi, C, Hasegawa, M, Takao, M, Sakai, M, Akagi, M, Iwasaki, Y, Yoshida, M, Scheres, S.H.W, Goedert, M.
登録日2023-01-24
公開日2023-11-08
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Acta Neuropathol Commun, 11, 2023
5N9Y
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The full-length structure of ZntB
分子名称: Zinc transport protein ZntB
著者Cornelius, G, Stetsenko, A, Scheres, S.H.W, Slotboom, D.J, Guskov, A.
登録日2017-02-27
公開日2017-11-15
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The structural basis of proton driven zinc transport by ZntB.
Nat Commun, 8, 2017
5NIK
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BU of 5nik by Molmil
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump
分子名称: Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC
著者Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D.
登録日2017-03-24
公開日2017-05-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
5NIL
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Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump-MacB section
分子名称: Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC
著者Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D.
登録日2017-03-24
公開日2017-05-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
5O3L
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Paired helical filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3O
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Pronase-treated paired helical filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3T
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Straight filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
6HRF
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BU of 6hrf by Molmil
Straight filament from sporadic Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-09-26
公開日2018-10-10
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6GX5
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BU of 6gx5 by Molmil
Narrow Pick Filament from Pick's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-06-26
公開日2018-09-12
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
6HRE
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BU of 6hre by Molmil
Paired helical filament from sporadic Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-09-26
公開日2018-10-10
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
7ARE
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BU of 7are by Molmil
DNA origami pointer object v2
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Thomas, M, Feigl, E, Kohler, F, Kube, M, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-24
公開日2020-11-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7AS5
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BU of 7as5 by Molmil
126 helix bundle DNA nanostructure
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-27
公開日2020-11-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7ART
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BU of 7art by Molmil
48 helix bundle DNA origami brick
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Feigl, E, Kube, M, Kohler, F, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-26
公開日2020-11-11
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7ARV
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BU of 7arv by Molmil
TwistTower_native-twist
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-26
公開日2020-11-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7ARY
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BU of 7ary by Molmil
Twist-Tower_twist-corrected-variant
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-26
公開日2020-11-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
6ZWV
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BU of 6zwv by Molmil
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: 3 Closed RBDs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Ke, Z, Qu, K, Nakane, T, Xiong, X, Cortese, M, Zila, V, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-28
公開日2020-08-05
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and distributions of SARS-CoV-2 spike proteins on intact virions.
Nature, 588, 2020
6ZP0
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Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-08
公開日2020-07-22
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020

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