8BYN
Chronic traumatic encephalopathy tau filaments with PET ligand flortaucipir
Summary for 8BYN
| Entry DOI | 10.2210/pdb8byn/pdb |
| EMDB information | 16329 |
| Descriptor | Microtubule-associated protein tau, 7-(6-fluoranylpyridin-3-yl)-5~{H}-pyrido[4,3-b]indole (2 entities in total) |
| Functional Keywords | chronic traumatic encephalopathy, primary age-related tauopathy, tau filaments, pet ligand, flortaucipir, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 277098.84 |
| Authors | Shi, Y.,Ghetti, B.,Goedert, M.,Scheres, S.H.W. (deposition date: 2022-12-13, release date: 2023-01-11, Last modification date: 2023-11-01) |
| Primary citation | Shi, Y.,Ghetti, B.,Goedert, M.,Scheres, S.H.W. Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir. J.Mol.Biol., 435:168025-168025, 2023 Cited by PubMed: 37330290DOI: 10.1016/j.jmb.2023.168025 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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