8CAX

Structure of Tau filaments Type II from Subacute Sclerosing Panencephalitis

Summary for 8CAX

• Entry DOI: 10.2210/pdb8cax/pdb
• Related: 8CAQ
• EMDB information: 16535
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: tau filament, sspe, neurodegenerative disease, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 275519.23

Authors

Qi, C.,Hasegawa, M.,Takao, M.,Sakai, M.,Akagi, M.,Iwasaki, Y.,Yoshida, M.,Scheres, S.H.W.,Goedert, M. (deposition date: 2023-01-24, release date: 2023-11-08)

• Primary citation: Qi, C.,Hasegawa, M.,Takao, M.,Sakai, M.,Sasaki, M.,Mizutani, M.,Akagi, A.,Iwasaki, Y.,Miyahara, H.,Yoshida, M.,Scheres, S.H.W.,Goedert, M.; Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.; Acta Neuropathol Commun, 11:74-74, 2023; PubMed: 37143123; DOI: 10.1186/s40478-023-01565-2

Experimental method

ELECTRON MICROSCOPY (3.7 Å)