6SRI

Structure of the Fanconi anaemia core complex

Summary for 6SRI

• Entry DOI: 10.2210/pdb6sri/pdb
• EMDB information: 10290
• Descriptor: Unassigned secondary structure elements (central region, proposed FANCB-FAAP100: chain A,a; base region, proposed FANCC-FANC-E-FANCF: chain 3), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (proposed FANCB), ... (27 entities in total)
• Functional Keywords: fanconi anaemia core complex; e3 ligase; dna repair, ligase
• Biological source: Gallus gallus; More
• Total number of polymer chains: 47
• Total formula weight: 375465.51

Authors

Shakeel, S.,Rajendra, E.,Alcon, P.,He, S.,Scheres, S.H.W.,Passmore, L.A. (deposition date: 2019-09-05, release date: 2019-11-06, Last modification date: 2019-11-20)

• Primary citation: Shakeel, S.,Rajendra, E.,Alcon, P.,O'Reilly, F.,Chorev, D.S.,Maslen, S.,Degliesposti, G.,Russo, C.J.,He, S.,Hill, C.H.,Skehel, J.M.,Scheres, S.H.W.,Patel, K.J.,Rappsilber, J.,Robinson, C.V.,Passmore, L.A.; Structure of the Fanconi anaemia monoubiquitin ligase complex.; Nature, 575:234-237, 2019; PubMed: 31666700; DOI: 10.1038/s41586-019-1703-4

Experimental method

ELECTRON MICROSCOPY (4.2 Å)