3LSE
 
 | |
4W64
 | |
3LSD
 | | N-Domain of human adhesion/growth-regulatory galectin-9 | | 分子名称: | Galectin-9 | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2010-02-12 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution.
Int.J.Biochem.Cell Biol., 42, 2010
|
|
6BHJ
 | | Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer | | 分子名称: | 38-MER RNA-DNA Aptamer, GLYCEROL, HIV-1 REVERSE TRANSCRIPTASE P51 subunit, ... | | 著者 | Ruiz, F.X, Miller, M.T, Tuske, S, Das, K, Arnold, E. | | 登録日 | 2017-10-30 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Integrative Structural Biology Studies of HIV-1 Reverse Transcriptase Binding to a High-Affinity DNA Aptamer
Curr Res Struct Biol, 2020
|
|
6O9E
 | | Structure of HIV-1 Reverse Transcriptase in complex with DNA and INDOPY-1 | | 分子名称: | 5-methyl-1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrido[3,2-b]indole-3-carbonitrile, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Ruiz, F.X, Hoang, A, Das, K, Arnold, E. | | 登録日 | 2019-03-13 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of HIV-1 Inhibition by Nucleotide-Competing Reverse Transcriptase Inhibitor INDOPY-1.
J.Med.Chem., 62, 2019
|
|
8RTH
 | | Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase | | 分子名称: | 3-methylcrotonyl-CoA carboxylase, putative, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ... | | 著者 | Ruiz, F.M, Plaza-Pegueroles, A, Fernandez-Tornero, C. | | 登録日 | 2024-01-26 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | | 主引用文献 | The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function.
Structure, 2024
|
|
5JP5
 | | Crystal structure of rat Galectin 5 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Galectin-5 | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2016-05-03 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Characterization of Rat Galectin-5, an N-Tailed Monomeric Proto-Type-like Galectin.
Biomolecules, 11, 2021
|
|
6Y4R
 | |
7P8H
 | | chicken GRIFIN bound to blood group tetrasaccharide B (type 1) | | 分子名称: | Galectin, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2021-07-22 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Structural Characterization of Rat Galectin-5, an N-Tailed Monomeric Proto-Type-like Galectin.
Biomolecules, 11, 2021
|
|
6TUX
 | | human XPG-DNA, Complex 2 | | 分子名称: | DNA (5'-D(P*AP*AP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*AP*GP*TP*T)-3'), DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells | | 著者 | Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2020-01-08 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
|
|
4WVV
 | |
4WVW
 | |
6UL5
 | | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with 4-[(4-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy}thieno[3,2-d]pyrimidin-2-yl)amino]-2-fluorobenzonitrile (24b), a non-nucleoside RT inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 4-[(4-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy}thieno[3,2-d]pyrimidin-2-yl)amino]-2-fluorobenzonitrile, MAGNESIUM ION, ... | | 著者 | Ruiz, F.X, Pilch, A, Arnold, E. | | 登録日 | 2019-10-06 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel.
J.Med.Chem., 63, 2020
|
|
2PZN
 | | The crystallographic structure of Aldose Reductase IDD393 complex confirms Leu300 as a specificity determinant | | 分子名称: | (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Ruiz, F, Hazemann, I, Darmanin, C, Mitschler, A, Van Zandt, M, Joachimiak, A, El-Kabbani, O, Podjarny, A. | | 登録日 | 2007-05-18 | | 公開日 | 2008-05-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | The Crystallographic Structure of Alr2-Idd393 Complex Confirms Leu300 as a Specificity Determinant
To be Published
|
|
5M2F
 | | Crystal structure of human AKR1B10 complexed with NADP+ and the synthetic retinoid UVI2008 | | 分子名称: | 1,2-ETHANEDIOL, 3-bromo-4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid, Aldo-keto reductase family 1 member B10, ... | | 著者 | Ruiz, F.X, Cousido-Siah, A, Mitschler, A, Porte, S, Alvarez, S, Dominguez, M, Alvarez, R, de Lera, A.R, Pares, X, Farres, J, Podjarny, A. | | 登録日 | 2016-10-12 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.503 Å) | | 主引用文献 | Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008.
Chem. Biol. Interact., 276, 2017
|
|
5NLD
 | | Chicken GRIFIN (crystallisation pH: 7.5) | | 分子名称: | Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2017-04-04 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | Chicken GRIFIN: Structural characterization in crystals and in solution.
Biochimie, 146, 2018
|
|
5NLE
 | | Chicken GRIFIN (crystallisation pH: 8.0) | | 分子名称: | Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2017-04-04 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.845 Å) | | 主引用文献 | Chicken GRIFIN: Structural characterization in crystals and in solution.
Biochimie, 146, 2018
|
|
5NLH
 | | Chicken GRIFIN (crystallisation pH: 8.5) | | 分子名称: | Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2017-04-04 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Chicken GRIFIN: Structural characterization in crystals and in solution.
Biochimie, 146, 2018
|
|
5NLZ
 | |
5NM6
 | |
6TUW
 | | human XPG-DNA, Complex 1 | | 分子名称: | DNA (5'-D(P*GP*AP*AP*CP*TP*CP*TP*G)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*AP*GP*TP*TP*C)-3'), DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells | | 著者 | Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2020-01-08 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
|
|
5NMJ
 | | Chicken GRIFIN (crystallisation pH: 6.5) | | 分子名称: | Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2017-04-06 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Chicken GRIFIN: Structural characterization in crystals and in solution.
Biochimie, 146, 2018
|
|
5NM1
 | | Chicken GRIFIN (crystallisation pH: 6.2) | | 分子名称: | Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ruiz, F.M, Romero, A. | | 登録日 | 2017-04-05 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Chicken GRIFIN: Structural characterization in crystals and in solution.
Biochimie, 146, 2018
|
|
7KWU
 | | Crystal Structure of HIV-1 RT in Complex with 16c (K07-15) | | 分子名称: | 1,2-ETHANEDIOL, 4-[(4-{[4-(4-cyano-2,6-dimethylphenoxy)-5-(pyridin-4-yl)pyrimidin-2-yl]amino}piperidin-1-yl)methyl]benzamide, MAGNESIUM ION, ... | | 著者 | Ruiz, F.X, Arnold, E. | | 登録日 | 2020-12-02 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | 2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 NNRTIs: Rational Design, Synthesis, Activity Evaluation, and Crystallographic Studies.
J.Med.Chem., 64, 2021
|
|
6TUS
 | | human XPG, Apo2 form | | 分子名称: | DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells, GLYCEROL, SULFATE ION | | 著者 | Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2020-01-08 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
|
|
