3LSE

N-Domain of human adhesion/growth-regulatory galectin-9 in complex with lactose

Summary for 3LSE

• Entry DOI: 10.2210/pdb3lse/pdb
• Related: 3LSD
• Related PRD ID: PRD_900004
• Descriptor: Galectin-9, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: mainly beta, alternative splicing, cytoplasm, lectin, polymorphism, secreted, sugar binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 16207.07

Authors

Ruiz, F.M.,Romero, A. (deposition date: 2010-02-12, release date: 2010-05-05, Last modification date: 2023-09-06)

• Primary citation: Solis, D.,Mate, M.J.,Lohr, M.,Ribeiro, J.P.,Lopez-Merino, L.,Andre, S.,Buzamet, E.,Canada, F.J.,Kaltner, H.,Lensch, M.,Ruiz, F.M.,Haroske, G.,Wollina, U.,Kloor, M.,Kopitz, J.,Saiz, J.L.,Menendez, M.,Jimenez-Barbero, J.,Romero, A.,Gabius, H.J.; N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution.; Int.J.Biochem.Cell Biol., 42:1019-1029, 2010; PubMed: 20227520; DOI: 10.1016/j.biocel.2010.03.007

Experimental method

X-RAY DIFFRACTION (2.69 Å)