6BHJ

Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer

Summary for 6BHJ

• Entry DOI: 10.2210/pdb6bhj/pdb
• Related: 5D3G
• Related PRD ID: PRD_900003
• Descriptor: HIV-1 REVERSE TRANSCRIPTASE P66 subunit, HIV-1 REVERSE TRANSCRIPTASE P51 subunit, 38-MER RNA-DNA Aptamer, ... (8 entities in total)
• Functional Keywords: human immunodeficiency virus 1, rna-directed dna polymerase, protein/rna/dna, aptamer, transferase, transferase-dna complex, transferase/dna
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 257302.41

Authors

Ruiz, F.X.,Miller, M.T.,Tuske, S.,Das, K.,Arnold, E. (deposition date: 2017-10-30, release date: 2018-10-31, Last modification date: 2023-10-04)

• Primary citation: Tuske, S.,Zheng, J.,Olson, E.D.,Ruiz, F.X.,Pascal, B.D.,Bauman, J.D.,Das, K.,DeStefano, J.J.,Musier-Forsyth, K.,Griffin, P.R.,Arnold, E.; Integrative Structural Biology Studies of HIV-1 Reverse Transcriptase Binding to a High-Affinity DNA Aptamer; Curr Res Struct Biol, 2020; DOI: 10.1016/j.crstbi.2020.06.002

Experimental method

X-RAY DIFFRACTION (2.81 Å)