7KWU
Crystal Structure of HIV-1 RT in Complex with 16c (K07-15)
Summary for 7KWU
Entry DOI | 10.2210/pdb7kwu/pdb |
Descriptor | Reverse transcriptase p66, Reverse transcriptase p51, SULFATE ION, ... (7 entities in total) |
Functional Keywords | human immunodeficiency virus 1, non nucleotide-reverse transcriptase inhibitor, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Total number of polymer chains | 2 |
Total formula weight | 115530.42 |
Authors | Ruiz, F.X.,Arnold, E. (deposition date: 2020-12-02, release date: 2021-03-31, Last modification date: 2023-10-18) |
Primary citation | Kang, D.,Ruiz, F.X.,Sun, Y.,Feng, D.,Jing, L.,Wang, Z.,Zhang, T.,Gao, S.,Sun, L.,De Clercq, E.,Pannecouque, C.,Arnold, E.,Zhan, P.,Liu, X. 2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 NNRTIs: Rational Design, Synthesis, Activity Evaluation, and Crystallographic Studies. J.Med.Chem., 64:4239-4256, 2021 Cited by PubMed: 33734714DOI: 10.1021/acs.jmedchem.1c00268 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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