7UDC
 
 | | cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1 | | 分子名称: | Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1 | | 著者 | Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X. | | 登録日 | 2022-03-18 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex.
Sci Adv, 8, 2022
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7UDB
 | | Cryo-EM structure of a synaptobrevin-Munc18-1-syntaxin-1 complex class 2 | | 分子名称: | Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1 | | 著者 | Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X. | | 登録日 | 2022-03-18 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex.
Sci Adv, 8, 2022
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8U27
 | | Bcl-2-xL complexed with compound 35 | | 分子名称: | Apoptosis regulator Bcl-2, Bcl-2-like protein 1 chimera, propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate | | 著者 | Rizo, J, Pan, Y.-Z. | | 登録日 | 2023-09-05 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights for selective disruption of Beclin 1 binding to Bcl-2.
Commun Biol, 6, 2023
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2Q3X
 | | The RIM1alpha C2B domain | | 分子名称: | CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ... | | 著者 | Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J. | | 登録日 | 2007-05-30 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution.
Biochemistry, 46, 2007
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1HS7
 | | VAM3P N-TERMINAL DOMAIN SOLUTION STRUCTURE | | 分子名称: | SYNTAXIN VAM3 | | 著者 | Dulubova, I, Yamaguchi, T, Wang, Y, Sudhof, T.C, Rizo, J. | | 登録日 | 2000-12-24 | | 公開日 | 2001-03-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Vam3p structure reveals conserved and divergent properties of syntaxins.
Nat.Struct.Biol., 8, 2001
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4Y21
 | | Crystal Structure of Munc13-1 MUN domain | | 分子名称: | Protein unc-13 homolog A | | 著者 | Yang, X.Y, Wang, S, Sheng, Y, Zhang, M, Zou, W.J, Wu, L.J, Kang, L.J, Rizo, J, Zhang, R.G, Xu, T, Ma, C. | | 登録日 | 2015-02-09 | | 公開日 | 2015-06-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming.
Nat.Struct.Mol.Biol., 22, 2015
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2A4H
 | | Solution structure of Sep15 from Drosophila melanogaster | | 分子名称: | Selenoprotein Sep15 | | 著者 | Ferguson, A.D, Labunskyy, V.M, Fomenko, D.E, Chelliah, Y, Amezcua, C.A, Rizo, J, Gladyshev, V.N, Deisenhofer, J. | | 登録日 | 2005-06-28 | | 公開日 | 2005-12-13 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family.
J.Biol.Chem., 281, 2006
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2A20
 | | Solution structure of Rim2 Zinc Finger Domain | | 分子名称: | Regulating synaptic membrane exocytosis protein 2, ZINC ION | | 著者 | Dulubova, I, Lou, X, Lu, J, Huryeva, I, Alam, A, Schneggenburger, R, Sudhof, T.C, Rizo, J. | | 登録日 | 2005-06-21 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?
Embo J., 24, 2005
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2A2P
 | | Solution structure of SelM from Mus musculus | | 分子名称: | Selenoprotein M | | 著者 | Ferguson, A.D, Labunskyy, V.M, Fomenko, D.E, Chelliah, Y, Amezcua, C.A, Rizo, J, Gladyshev, V.N, Deisenhofer, J. | | 登録日 | 2005-06-22 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family.
J.Biol.Chem., 281, 2006
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5UF7
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3N5A
 | | Synaptotagmin-7, C2B-domain, calcium bound | | 分子名称: | CALCIUM ION, Synaptotagmin-7 | | 著者 | Tomchick, D.R, Rizo, J, Craig, T.K. | | 登録日 | 2010-05-24 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.441 Å) | | 主引用文献 | Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.
Plos One, 5, 2010
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6ANK
 | | Synaptotagmin-7, C2A- and C2B-domains | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 | | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | | 登録日 | 2017-08-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.254 Å) | | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6ANJ
 | | Synaptotagmin-7, C2A domain | | 分子名称: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | | 登録日 | 2017-08-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3SWH
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5UE8
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2CJS
 | | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, ... | | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | | 登録日 | 2006-04-06 | | 公開日 | 2006-06-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch.
Plos Biol., 4, 2006
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2CJT
 | | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, UNC-13 HOMOLOG A | | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | | 登録日 | 2006-04-06 | | 公開日 | 2006-06-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch
Plos Biol., 4, 2006
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2JQQ
 | | Solution structure of Saccharomyces cerevisiae conserved oligomeric Golgi subunit 2 protein (Cog2p) | | 分子名称: | Conserved oligomeric Golgi complex subunit 2 | | 著者 | Cavanaugh, L.F, Chen, X, Pelczer, I, Rizo, J, Hughson, F.M. | | 登録日 | 2007-06-06 | | 公開日 | 2007-06-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of conserved oligomeric Golgi complex subunit 2
J.Biol.Chem., 282, 2007
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1EHS
 | | THE STRUCTURE OF ESCHERICHIA COLI HEAT-STABLE ENTEROTOXIN B BY NUCLEAR MAGNETIC RESONANCE AND CIRCULAR DICHROISM | | 分子名称: | HEAT-STABLE ENTEROTOXIN B | | 著者 | Sukumar, M, Rizo, J, Wall, M, Dreyfus, L.A, Kupersztoch, Y.M, Gierasch, L.M. | | 登録日 | 1995-06-13 | | 公開日 | 1995-09-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of Escherichia coli heat-stable enterotoxin b by nuclear magnetic resonance and circular dichroism.
Protein Sci., 4, 1995
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1BR0
 | | THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A | | 分子名称: | PROTEIN (SYNTAXIN 1-A) | | 著者 | Fernandez, I, Ubach, J, Dubulova, I, Zhang, X, Sudhof, T.C, Rizo, J. | | 登録日 | 1998-08-25 | | 公開日 | 1998-09-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Cell(Cambridge,Mass.), 94, 1998
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1BYN
 | | SOLUTION STRUCTURE OF THE CALCIUM-BOUND FIRST C2-DOMAIN OF SYNAPTOTAGMIN I | | 分子名称: | CALCIUM ION, PROTEIN (SYNAPTOTAGMIN I) | | 著者 | Shao, X, Fernandez, I, Sudhof, T.C, Rizo, J. | | 登録日 | 1998-10-18 | | 公開日 | 1998-10-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
Biochemistry, 37, 1998
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2BWQ
 | | Crystal Structure of the RIM2 C2A-domain at 1.4 angstrom Resolution | | 分子名称: | REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, SULFATE ION | | 著者 | Dai, H, Tomchick, D.R, Garcia, J, Sudhof, T.C, Machius, M, Rizo, J. | | 登録日 | 2005-07-15 | | 公開日 | 2005-10-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Crystal Structure of the Rim2 C(2)A-Domain at 1.4 A Resolution.
Biochemistry, 44, 2005
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2VFX
 | | Structure of the Symmetric Mad2 Dimer | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... | | 著者 | Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X. | | 登録日 | 2007-11-05 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
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4DBB
 | | The PTB domain of Mint1 is autoinhibited by a helix in the C-terminal linker region | | 分子名称: | ACETIC ACID, Amyloid beta A4 precursor protein-binding family A member 1, CHLORIDE ION, ... | | 著者 | Tomchick, D.R, Rizo, J, Ho, A, Xu, Y. | | 登録日 | 2012-01-13 | | 公開日 | 2012-03-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6NYT
 | | Munc13-1 C2B-domain, calcium bound | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | | 登録日 | 2019-02-12 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.369 Å) | | 主引用文献 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.
Nat. Struct. Mol. Biol., 17, 2010
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