6ANK

Synaptotagmin-7, C2A- and C2B-domains

Summary for 6ANK
DescriptorSynaptotagmin-7, 1,2-ETHANEDIOL, CALCIUM ION, ... (4 entities in total)
Functional Keywordscalcium/phospholipid binding protein, protein binding
Biological sourceRattus norvegicus (Rat)
Cellular locationCell membrane ; Single-pass membrane protein : Q62747
Total number of polymer chains2
Total formula weight66577.31
Authors
Tomchick, D.R.,Rizo, J.,Voleti, R. (deposition date: 2017-08-13, release date: 2017-09-20, Last modification date: 2017-11-08)
Primary citationRizo, J.,Sudhof, T.C.,Tomchick, D.R.,Voleti, R.
Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114:E8518-E8527, 2017
PubMed: 28923929
DOI: 110.1073/pnas.1710708114
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.254 Å)
Structure validation
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PDB entries from 2021-06-16