4DBB

The PTB domain of Mint1 is autoinhibited by a helix in the C-terminal linker region

Summary for 4DBB

• Entry DOI: 10.2210/pdb4dbb/pdb
• Descriptor: Amyloid beta A4 precursor protein-binding family A member 1, CHLORIDE ION, ACETIC ACID, ... (6 entities in total)
• Functional Keywords: x11s/mints, ptb domain, chimera protein, protein transport
• Biological source: Rattus norvegicus (Rat); More
• Cellular location: Cytoplasm . Isoform 2: Golgi apparatus : O35430
• Total number of polymer chains: 1
• Total formula weight: 18868.80

Authors

Tomchick, D.R.,Rizo, J.,Ho, A.,Xu, Y. (deposition date: 2012-01-13, release date: 2012-03-07, Last modification date: 2024-02-28)

• Primary citation: Matos, M.F.,Xu, Y.,Dulubova, I.,Otwinowski, Z.,Richardson, J.M.,Tomchick, D.R.,Rizo, J.,Ho, A.; Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing.; Proc.Natl.Acad.Sci.USA, 109:3802-3807, 2012; PubMed: 22355143; DOI: 10.1073/pnas.1119075109

Experimental method

X-RAY DIFFRACTION (1.901 Å)