1P2Z
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![BU of 1p2z by Molmil](/molmil-images/mine/1p2z) | Refinement of Adenovirus Type 2 Hexon with CNS | Descriptor: | CITRIC ACID, Hexon protein | Authors: | Rux, J.J, Kuser, P.R, Burnett, R.M. | Deposit date: | 2003-04-16 | Release date: | 2003-11-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and phylogenetic analysis of adenovirus hexons by use of
high-resolution x-ray crystallographic, molecular modeling, and sequence-based
methods J.VIROL., 77, 2003
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1FE2
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![BU of 1fe2 by Molmil](/molmil-images/mine/1fe2) | CRYSTAL STRUCTURE OF DIHOMO-GAMMA-LINOLEIC ACID BOUND IN THE CYCLOOXYGENASE CHANNEL OF PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EICOSA-8,11,14-TRIENOIC ACID, PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1, ... | Authors: | Thuresson, E.D, Malkowski, M.G, Lakkides, K.M, Smith, W.L, Garavito, R.M. | Deposit date: | 2000-07-20 | Release date: | 2001-05-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases. J.Biol.Chem., 276, 2001
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2SPL
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![BU of 2spl by Molmil](/molmil-images/mine/2spl) | A NOVEL SITE-DIRECTED MUTANT OF MYOGLOBIN WITH AN UNUSUALLY HIGH O2 AFFINITY AND LOW AUTOOXIDATION RATE | Descriptor: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Quillin, M.L, Arduini, R.M, Phillips Jr, G.N. | Deposit date: | 1993-08-25 | Release date: | 1994-01-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A novel site-directed mutant of myoglobin with an unusually high O2 affinity and low autooxidation rate. J.Biol.Chem., 267, 1992
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2TDM
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![BU of 2tdm by Molmil](/molmil-images/mine/2tdm) | STRUCTURE OF THYMIDYLATE SYNTHASE | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Finer-Moore, J, Stroud, R.M. | Deposit date: | 1997-03-28 | Release date: | 1997-08-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei. J.Mol.Biol., 232, 1993
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2TDD
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![BU of 2tdd by Molmil](/molmil-images/mine/2tdd) | STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE | Descriptor: | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-HYDROXYMETHYLENE-6-HYDROFOLIC ACID, THYMIDYLATE SYNTHASE | Authors: | Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M. | Deposit date: | 1993-04-05 | Release date: | 1993-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32, 1993
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1JMG
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1TSX
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![BU of 1tsx by Molmil](/molmil-images/mine/1tsx) | THYMIDYLATE SYNTHASE R179E MUTANT | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Finer-Moore, J, Stroud, R.M. | Deposit date: | 1995-12-05 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase. Protein Eng., 9, 1996
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7CQ2
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![BU of 7cq2 by Molmil](/molmil-images/mine/7cq2) | Crystal structure of Slx1-Slx4 | Descriptor: | GLYCEROL, SLX4 isoform 1, Structure-specific endonuclease subunit SLX1, ... | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | Deposit date: | 2020-08-08 | Release date: | 2021-06-16 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
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7CQ3
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![BU of 7cq3 by Molmil](/molmil-images/mine/7cq3) | Crystal structure of Slx1-Slx4 | Descriptor: | SLX4 isoform 1, SULFATE ION, Structure-specific endonuclease subunit SLX1, ... | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | Deposit date: | 2020-08-08 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
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7CQ4
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![BU of 7cq4 by Molmil](/molmil-images/mine/7cq4) | Crystal structure of Slx1-Slx4 in complex with 5'flap DNA | Descriptor: | DNA (27-MER), DNA (5'-D(*AP*GP*GP*AP*CP*AP*TP*CP*TP*TP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*TP*AP*CP*AP*AP*CP*AP*GP*AP*T)-3'), ... | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | Deposit date: | 2020-08-08 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.294 Å) | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
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1TVU
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![BU of 1tvu by Molmil](/molmil-images/mine/1tvu) | |
2NG1
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![BU of 2ng1 by Molmil](/molmil-images/mine/2ng1) | N AND GTPASE DOMAINS OF THE SIGNAL SEQUENCE RECOGNITION PROTEIN FFH FROM THERMUS AQUATICUS | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Freymann, D.M, Stroud, R.M, Walter, P. | Deposit date: | 1998-09-11 | Release date: | 1999-07-30 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP. Nat.Struct.Biol., 6, 1999
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1JMF
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![BU of 1jmf by Molmil](/molmil-images/mine/1jmf) | |
2BFZ
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![BU of 2bfz by Molmil](/molmil-images/mine/2bfz) | Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized. | Descriptor: | AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ... | Authors: | Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M. | Deposit date: | 2004-12-16 | Release date: | 2005-03-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism Biochemistry, 44, 2005
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1JMH
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![BU of 1jmh by Molmil](/molmil-images/mine/1jmh) | |
1JMI
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2BG2
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![BU of 2bg2 by Molmil](/molmil-images/mine/2bg2) | Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in the buffer. 1mM DTT and 1mM TCEP- HCl were used as reducing agents. Cys221 is reduced. | Descriptor: | BETA-LACTAMASE II, CHLORIDE ION, GLYCEROL, ... | Authors: | Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M. | Deposit date: | 2004-12-16 | Release date: | 2005-03-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism. Biochemistry, 44, 2005
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1PGG
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![BU of 1pgg by Molmil](/molmil-images/mine/1pgg) | PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), TRANS MODEL | Descriptor: | 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Loll, P.J, Picot, D, Garavito, R.M. | Deposit date: | 1995-12-02 | Release date: | 1997-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site. Biochemistry, 35, 1996
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1TVV
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![BU of 1tvv by Molmil](/molmil-images/mine/1tvv) | |
1TVW
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1TSZ
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![BU of 1tsz by Molmil](/molmil-images/mine/1tsz) | THYMIDYLATE SYNTHASE R179K MUTANT | Descriptor: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | Authors: | Finer-Moore, J, Stroud, R.M. | Deposit date: | 1995-12-05 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase. Protein Eng., 9, 1996
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1TSW
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![BU of 1tsw by Molmil](/molmil-images/mine/1tsw) | THYMIDYLATE SYNTHASE R179A MUTANT | Descriptor: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | Authors: | Finer-Moore, J, Stroud, R.M. | Deposit date: | 1995-12-05 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase. Protein Eng., 9, 1996
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8FVZ
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![BU of 8fvz by Molmil](/molmil-images/mine/8fvz) | PiPT Y150A | Descriptor: | CITRATE ANION, PHOSPHATE ION, Phosphate transporter | Authors: | Gupta, M, Finer-Moore, J, Stroud, R.M. | Deposit date: | 2023-01-20 | Release date: | 2024-01-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Roles of PiPT residues in phosphate binding and transport tested by mutagenesis To be published
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2BG7
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![BU of 2bg7 by Molmil](/molmil-images/mine/2bg7) | Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized. | Descriptor: | BETA-LACTAMASE II, GLYCEROL, SULFATE ION, ... | Authors: | Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M. | Deposit date: | 2004-12-17 | Release date: | 2005-03-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism Biochemistry, 44, 2005
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2BFL
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![BU of 2bfl by Molmil](/molmil-images/mine/2bfl) | Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent. | Descriptor: | AZIDE ION, GLYCEROL, Metallo-beta-lactamase type 2, ... | Authors: | Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M. | Deposit date: | 2004-12-08 | Release date: | 2005-03-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism Biochemistry, 44, 2005
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