1IGX
Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
Summary for 1IGX
Entry DOI | 10.2210/pdb1igx/pdb |
Related | 1DIY 1FE2 1IGZ |
Descriptor | Prostaglandin Endoperoxide H Synthase-1, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | membrane protein, fatty acid, eicosapentanoic acid, oxidoreductase, peroxidase, dioxygenase |
Biological source | Ovis aries (sheep) |
Total number of polymer chains | 1 |
Total formula weight | 69611.36 |
Authors | Malkowski, M.G.,Thuresson, E.D.,Smith, W.L.,Garavito, R.M. (deposition date: 2001-04-18, release date: 2001-12-12, Last modification date: 2023-08-16) |
Primary citation | Malkowski, M.G.,Thuresson, E.D.,Lakkides, K.M.,Rieke, C.J.,Micielli, R.,Smith, W.L.,Garavito, R.M. Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1. J.Biol.Chem., 276:37547-37555, 2001 Cited by PubMed: 11477109DOI: 10.1074/jbc.M105982200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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