1DIY
CRYSTAL STRUCTURE OF ARACHIDONIC ACID BOUND IN THE CYCLOOXYGENASE ACTIVE SITE OF PGHS-1
Summary for 1DIY
Entry DOI | 10.2210/pdb1diy/pdb |
Related | 1CVU 1DDX 1PGE 1PRH 1PTH |
Descriptor | PROSTAGLANDIN H2 SYNTHASE-1, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | arachidonic acid, membrane protein, peroxidase, dioxygenase, oxidoreductase |
Biological source | Ovis aries (sheep) |
Total number of polymer chains | 1 |
Total formula weight | 67577.28 |
Authors | Malkowski, M.G.,Ginell, S.L.,Smith, W.L.,Garavito, R.M. (deposition date: 1999-11-30, release date: 2000-09-22, Last modification date: 2023-08-09) |
Primary citation | Malkowski, M.G.,Ginell, S.L.,Smith, W.L.,Garavito, R.M. The productive conformation of arachidonic acid bound to prostaglandin synthase. Science, 289:1933-1937, 2000 Cited by PubMed: 10988074DOI: 10.1126/science.289.5486.1933 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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