1DIY

CRYSTAL STRUCTURE OF ARACHIDONIC ACID BOUND IN THE CYCLOOXYGENASE ACTIVE SITE OF PGHS-1

Summary for 1DIY

Entry DOI	10.2210/pdb1diy/pdb
Related	1CVU 1DDX 1PGE 1PRH 1PTH
Descriptor	PROSTAGLANDIN H2 SYNTHASE-1, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	arachidonic acid, membrane protein, peroxidase, dioxygenase, oxidoreductase
Biological source	Ovis aries (sheep)
Total number of polymer chains	1
Total formula weight	67577.28
Authors	Malkowski, M.G.,Ginell, S.L.,Smith, W.L.,Garavito, R.M. (deposition date: 1999-11-30, release date: 2000-09-22, Last modification date: 2023-08-09)
Primary citation	Malkowski, M.G.,Ginell, S.L.,Smith, W.L.,Garavito, R.M. The productive conformation of arachidonic acid bound to prostaglandin synthase. Science, 289:1933-1937, 2000 Cited by PubMed: 10988074 DOI: 10.1126/science.289.5486.1933 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation