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PDB: 63 件

5GZN
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Structure of neutralizing antibody bound to Zika envelope protein
分子名称: Antibody Heavy chain, Antibody light chain, Genome polyprotein
著者Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F.
登録日2016-09-29
公開日2016-12-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
2HNX
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Crystal Structure of aP2
分子名称: ACETIC ACID, Fatty acid-binding protein, adipocyte, ...
著者Marr, E, Tardie, M, Carty, M, Brown Phillips, T, Qiu, X, Karam, G.
登録日2006-07-13
公開日2006-11-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2).
Acta Crystallogr.,Sect.F, 62, 2006
5GZO
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Structure of neutralizing antibody bound to Zika envelope protein
分子名称: Antibody heavy chain, Antibody light chain, Genome polyprotein
著者Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F.
登録日2016-09-29
公開日2017-01-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.755 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
2P4E
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Crystal Structure of PCSK9
分子名称: MERCURY (II) ION, Proprotein convertase subtilisin/kexin type 9
著者Cunningham, D, Danley, D.E, Geoghegan, F.K, Griffor, M.C, Hawkins, J.L, Qiu, X.
登録日2007-03-12
公開日2007-04-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia.
Nat.Struct.Mol.Biol., 14, 2007
4F2A
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Crystal structure of cholestryl esters transfer protein in complex with inhibitors
分子名称: (2R)-3-{[4-(4-chloro-3-ethylphenoxy)pyrimidin-2-yl][3-(1,1,2,2-tetrafluoroethoxy)benzyl]amino}-1,1,1-trifluoropropan-2-ol, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHLORIDE ION, ...
著者Liu, S, Qiu, X.
登録日2012-05-07
公開日2012-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.
J.Biol.Chem., 287, 2012
4HG5
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Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with oxaloacetate
分子名称: CACODYLATE ION, GLYCEROL, OXALOACETATE ION, ...
著者Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M.
登録日2012-10-07
公開日2013-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
4HG3
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Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with alpha-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, CACODYLATE ION, GLYCEROL, ...
著者Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M.
登録日2012-10-06
公開日2013-07-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
4H5U
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Structural insights into yeast Nit2: wild-type yeast Nit2
分子名称: CACODYLATE ION, GLYCEROL, Probable hydrolase NIT2
著者Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M.
登録日2012-09-18
公開日2013-07-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
4HGD
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Structural insights into yeast Nit2: C169S mutant of yeast Nit2 in complex with an endogenous peptide-like ligand
分子名称: CACODYLATE ION, GLYCEROL, N-(4-carboxy-4-oxobutanoyl)-L-cysteinylglycine, ...
著者Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M.
登録日2012-10-08
公開日2013-07-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D, 69, 2013
1A36
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TOPOISOMERASE I/DNA COMPLEX
分子名称: DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3'), TOPOISOMERASE I
著者Stewart, L, Redinbo, M.R, Qiu, X, Champoux, J.J, Hol, W.G.J.
登録日1998-01-29
公開日1998-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A model for the mechanism of human topoisomerase I.
Science, 279, 1998
1AT3
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HERPES SIMPLEX VIRUS TYPE II PROTEASE
分子名称: DIISOPROPYL PHOSPHONATE, HERPES SIMPLEX VIRUS TYPE II PROTEASE
著者Hoog, S, Smith, W.W, Qiu, X, Abdel-Meguid, S.S.
登録日1997-08-16
公開日1998-10-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Active site cavity of herpesvirus proteases revealed by the crystal structure of herpes simplex virus protease/inhibitor complex.
Biochemistry, 36, 1997
4Q9O
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Crystal structure of Upps + inhibitor
分子名称: 3-(2-chlorophenyl)-5-methyl-N-[4-(propan-2-yl)phenyl]-1,2-oxazole-4-carboxamide, Isoprenyl transferase, SULFATE ION
著者Liu, S, Qiu, X.
登録日2014-05-01
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.
Protein Sci., 24, 2015
4Q9M
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Crystal structure of UPPs in complex with FPP and an allosteric inhibitor
分子名称: 3-(2-chlorophenyl)-5-methyl-N-[4-(propan-2-yl)phenyl]-1,2-oxazole-4-carboxamide, CADMIUM ION, FARNESYL DIPHOSPHATE, ...
著者Liu, S, Qiu, X.
登録日2014-05-01
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.
Protein Sci., 24, 2015
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