4Q9M
Crystal structure of UPPs in complex with FPP and an allosteric inhibitor
Summary for 4Q9M
Entry DOI | 10.2210/pdb4q9m/pdb |
Related | 4Q9O |
Descriptor | Isoprenyl transferase, 3-(2-chlorophenyl)-5-methyl-N-[4-(propan-2-yl)phenyl]-1,2-oxazole-4-carboxamide, FARNESYL DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | undecaprenyl diphosphate synthase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Streptococcus pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 58926.01 |
Authors | |
Primary citation | Danley, D.E.,Baima, E.T.,Mansour, M.,Fennell, K.F.,Chrunyk, B.A.,Mueller, J.P.,Liu, S.,Qiu, X. Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase. Protein Sci., 24:20-26, 2015 Cited by PubMed: 25287857DOI: 10.1002/pro.2579 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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