4Q9O

Crystal structure of Upps + inhibitor

Summary for 4Q9O

• Entry DOI: 10.2210/pdb4q9o/pdb
• Related: 4Q9M
• Descriptor: Isoprenyl transferase, 3-(2-chlorophenyl)-5-methyl-N-[4-(propan-2-yl)phenyl]-1,2-oxazole-4-carboxamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: undecaprenyl diphosphate synthase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 56667.32

Authors

Liu, S.,Qiu, X. (deposition date: 2014-05-01, release date: 2014-10-15, Last modification date: 2024-02-28)

• Primary citation: Danley, D.E.,Baima, E.T.,Mansour, M.,Fennell, K.F.,Chrunyk, B.A.,Mueller, J.P.,Liu, S.,Qiu, X.; Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.; Protein Sci., 24:20-26, 2015; PubMed: 25287857; DOI: 10.1002/pro.2579

Experimental method

X-RAY DIFFRACTION (2.2 Å)