4Q9O
Crystal structure of Upps + inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008834 | molecular_function | ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity |
| A | 0016094 | biological_process | polyprenol biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0045547 | molecular_function | ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008834 | molecular_function | ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity |
| B | 0016094 | biological_process | polyprenol biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0045547 | molecular_function | ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 2ZW A 301 |
| Chain | Residue |
| A | MET49 |
| A | LEU102 |
| A | ALA129 |
| A | PHE143 |
| A | LEU52 |
| A | GLN53 |
| A | ALA71 |
| A | ILE87 |
| A | PRO91 |
| A | PHE94 |
| A | TYR98 |
| A | VAL99 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | GLY29 |
| A | ASN30 |
| A | GLY31 |
| A | ARG32 |
| A | ARG41 |
| A | HIS45 |
| A | ARG79 |
| A | HOH466 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 2ZW B 301 |
| Chain | Residue |
| B | MET49 |
| B | GLN53 |
| B | ALA71 |
| B | ILE87 |
| B | PRO91 |
| B | PHE94 |
| B | TYR98 |
| B | VAL99 |
| B | LEU102 |
| B | ALA129 |
| B | PHE143 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | ASN30 |
| B | GLY31 |
| B | ARG32 |
| B | ARG41 |
| B | HIS45 |
| B | ARG79 |
Functional Information from PROSITE/UniProt
| site_id | PS01066 |
| Number of Residues | 18 |
| Details | UPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. DLIIRTSGelRlSnFLPW |
| Chain | Residue | Details |
| A | ASP196-TRP213 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01139","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01139","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01139","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
