4Q9M
Crystal structure of UPPs in complex with FPP and an allosteric inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoprenyl transferase | polymer | 246 | 27882.8 | 2 | UniProt (Q8DRB3) Pfam (PF01255) | Streptococcus pneumoniae | |
| 2 | C, N (A, B) | 3-(2-chlorophenyl)-5-methyl-N-[4-(propan-2-yl)phenyl]-1,2-oxazole-4-carboxamide | non-polymer | 354.8 | 2 | Chemie (2ZW) | |||
| 3 | D, O (A, B) | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 2 | Chemie (FPP) | |||
| 4 | E, F, G, H, I... (A, B) | CADMIUM ION | non-polymer | 112.4 | 15 | Chemie (CD) | |||
| 5 | V, W (A, B) | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 252 (UniProt: Q8DRB3)
| PDB | External Database | Details |
|---|---|---|
| Gly 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Met 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55765.5 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 3160.5 | |
| All* | Total formula weight | 58926.0 |
