4F2A

Crystal structure of cholestryl esters transfer protein in complex with inhibitors

Summary for 4F2A

• Entry DOI: 10.2210/pdb4f2a/pdb
• Related: 4EWS
• Descriptor: Cholesteryl ester transfer protein, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTERYL OLEATE, ... (7 entities in total)
• Functional Keywords: cholestryl ester transfer protein, high-density lipoprotein, low-density lipoprotein, cholestryl ester transfer protein-inhibitor complex, lipid transport-inhibitor complex, lipid transport/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 56673.26

Authors

Liu, S.,Qiu, X. (deposition date: 2012-05-07, release date: 2012-09-05, Last modification date: 2020-07-29)

• Primary citation: Liu, S.,Mistry, A.,Reynolds, J.M.,Lloyd, D.B.,Griffor, M.C.,Perry, D.A.,Ruggeri, R.B.,Clark, R.W.,Qiu, X.; Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.; J.Biol.Chem., 287:37321-37329, 2012; PubMed: 22961980; DOI: 10.1074/jbc.M112.380063

Experimental method

X-RAY DIFFRACTION (3.11 Å)