4F2A

Crystal structure of cholestryl esters transfer protein in complex with inhibitors

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-BM
Synchrotron site	APS
Beamline	17-BM
Detector technology	CCD
Detector	MAR CCD 165 mm
Wavelength(s)	1
Spacegroup name	P 21 21 21
Unit cell lengths	68.772, 69.915, 187.145
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	38.880 - 3.110
R-factor	0.1855
Rwork	0.183
R-free	0.23890
Structure solution method	FOURIER SYNTHESIS
RMSD bond length	0.010
RMSD bond angle	1.350
Refinement software	BUSTER (2.11.2)

Data quality characteristics

	Overall
Low resolution limit [Å]	50.000
High resolution limit [Å]	3.100
Rmerge	0.111
Number of reflections	12770
Completeness [%]	76.2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1