4HGD

Structural insights into yeast Nit2: C169S mutant of yeast Nit2 in complex with an endogenous peptide-like ligand

Summary for 4HGD

Entry DOI	10.2210/pdb4hgd/pdb
Related	4H5U 4HG3 4HG5
Descriptor	Probable hydrolase NIT2, GLYCEROL, CACODYLATE ION, ... (5 entities in total)
Functional Keywords	nitrilase superfamily, omega-amidase, hydrolase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	4
Total formula weight	156081.33
Authors	Liu, H.,Qiu, X.,Zhang, M.,Gao, Y.,Niu, L.,Teng, M. (deposition date: 2012-10-08, release date: 2013-07-31, Last modification date: 2024-03-20)
Primary citation	Liu, H.,Gao, Y.,Zhang, M.,Qiu, X.,Cooper, A.J.L.,Niu, L.,Teng, M. Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69:1470-1481, 2013 Cited by PubMed: 23897470 DOI: 10.1107/S0907444913009347 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation