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PDB: 191 件
6P8M
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Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者Weidle, C, Pancera, M.
登録日2019-06-07
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.594 Å)
主引用文献Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
Cell Rep, 29, 2019
6WT3
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Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
分子名称: 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN
著者Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M.
登録日2020-05-01
公開日2020-07-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
J.Lipid Res., 61, 2020
6WN4
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Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
分子名称: 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN, Lipoprotein lipase peptide
著者Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M.
登録日2020-04-22
公開日2020-07-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
J.Lipid Res., 61, 2020
6VLW
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BU of 6vlw by Molmil
Crystal Structure of 426cOD in Complex with VRC01 Fab
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 426cOD, ...
著者Weidle, C, Pancera, M.
登録日2020-01-27
公開日2020-12-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献HIV-1 VRC01 Germline-Targeting Immunogens Select Distinct Epitope-Specific B Cell Receptors.
Immunity, 53, 2020
7RQQ
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BU of 7rqq by Molmil
Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP
分子名称: 1,2-ETHANEDIOL, F10 Heavy Chain, L9 Kappa Chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7RQP
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BU of 7rqp by Molmil
Structure of PfCSP NPNV binding antibody L9
分子名称: L9 Heavy Chain, L9 Kappa Chain
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7RQR
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Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP
分子名称: 1,2-ETHANEDIOL, F10 Kappa Chain, L9 Heavy Chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
1GPZ
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BU of 1gpz by Molmil
THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1R COMPONENT, ...
著者Budayova-Spano, M, Fontecilla-Camps, J.C, Gaboriaud, C.
登録日2001-11-15
公開日2002-07-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Crystal Structure of the Zymogen Catalytic Domain of Complement Protease C1R Reveals that a Disruptive Mechanical Stress is Required to Trigger Activation of the C1 Complex.
Embo J., 21, 2002
6U9U
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BU of 6u9u by Molmil
Structure of GM9_TH8seq732127 FAB
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ...
著者Singh, S, Liban, T.J, Pancera, M.
登録日2019-09-09
公開日2019-11-06
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
J.Exp.Med., 217, 2020
6XQW
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BU of 6xqw by Molmil
Crystal Structure of MaliM03 Fab in complex with Pfmsp1-19
分子名称: MaliM03 Fab Heavy Chain, MaliM03 Fab Light Chain, Pfmsp1-19
著者Singh, S, Pancera, M.
登録日2020-07-10
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.991 Å)
主引用文献Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites.
J.Exp.Med., 218, 2021
6OL6
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BU of 6ol6 by Molmil
Structure of iglb12 scFv in complex with anti-idiotype ib2 Fab
分子名称: CHLORIDE ION, ib2 Heavy Chain, ib2 Light Chain, ...
著者Weidle, C, Pancera, M, Gewe, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6MYY
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BU of 6myy by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
著者Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
登録日2018-11-02
公開日2018-11-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6MZJ
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BU of 6mzj by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
著者Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
登録日2018-11-05
公開日2018-11-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
8VRU
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BU of 8vru by Molmil
GII.4c apo norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein, FORMIC ACID
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2024-01-22
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Advancement of norovirus therapies
To Be Published
8Y6C
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BU of 8y6c by Molmil
Norovirus GII.10 P domain and 2'-FL (powder)
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GII.10 norovirus P domain in complex with 2'FL (powder), ...
著者Hansman, G, Tame, J.R.H, Kher, G, Pancera, M.
登録日2024-02-02
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Norovirus GII.10 P domain and 2'-FL (powder)
To Be Published
8VRV
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BU of 8vrv by Molmil
GII.4c H2-tri HBGA norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein, FORMIC ACID, ...
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2024-01-22
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Advancement of norovirus therapies
To Be Published
7ELL
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BU of 7ell by Molmil
In situ structure of capping enzyme lambda2, penetration protein mu1 of mammalian reovirus capsid asymmetric unit.
分子名称: MYRISTIC ACID, Mu1, mRNA (guanine-N(7)-)-methyltransferase
著者Zhou, Z.H, Pan, M.
登録日2021-04-12
公開日2021-10-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor mu2 and capsid proteins.
Nat Commun, 12, 2021
7ELH
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BU of 7elh by Molmil
In situ structure of transcriptional enzyme complex and capsid shell protein of mammalian reovirus at initiation state
分子名称: Lambda 1, Minor core protein mu2, PHOSPHATE ION, ...
著者Zhou, Z.H, Pan, M.
登録日2021-04-11
公開日2021-10-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor mu2 and capsid proteins.
Nat Commun, 12, 2021
1MD7
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BU of 1md7 by Molmil
Monomeric structure of the zymogen of complement protease C1r
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C1R COMPLEMENT SERINE PROTEASE
著者Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C.
登録日2002-08-07
公開日2003-08-07
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
Structure, 10, 2002
1MD8
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BU of 1md8 by Molmil
Monomeric structure of the active catalytic domain of complement protease C1r
分子名称: C1R COMPLEMENT SERINE PROTEASE
著者Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C.
登録日2002-08-07
公開日2003-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
Structure, 10, 2002
3M4X
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BU of 3m4x by Molmil
Structure of a ribosomal methyltransferase
分子名称: NOL1/NOP2/sun family protein
著者Galimand, M, Schmitt, E, Panvert, M, Mechulam, Y, Courvalin, P.
登録日2010-03-12
公開日2010-04-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structure of an RNA methyltransferase
To be Published
6VJN
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BU of 6vjn by Molmil
Structure of NHP D11A.B5Fab in complex with 16055 V2b peptide
分子名称: D11A.B5 Fab Heavy chain, D11A.B5 Fab Light chain, SODIUM ION, ...
著者Singh, S, Liban, T.J, Pancera, M.
登録日2020-01-16
公開日2021-01-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6VRQ
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BU of 6vrq by Molmil
Crystal structure of gl12A21 Fab in complex with anti-idiotypic iv12 Fab
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Aljedani, S.S, Weidle, C, Pancera, M.
登録日2020-02-08
公開日2021-02-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
6WAS
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BU of 6was by Molmil
Structure of D19.PA8 Fab in complex with 1FD6 16055 V1V2 scaffold
分子名称: 1FD6 16055 V1V2 scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, GN1_PA8 Fab Heavy chain, ...
著者Singh, S, Liban, T.J, Pancera, M.
登録日2020-03-26
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6WIT
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BU of 6wit by Molmil
Crystal structure of NHP D15.SD7 Fab in complex with 16055 V1V2 1FD6 scaffold
分子名称: 16055 V1V2 1FD6 Scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, NHP GN1-SD7 Fab Heavy Chain, ...
著者Liban, T, Aljedani, S, Rodarte, J, Pancera, M.
登録日2020-04-10
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021

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件を2024-07-17に公開中

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