1MD7

Monomeric structure of the zymogen of complement protease C1r

Summary for 1MD7

Entry DOI	10.2210/pdb1md7/pdb
Related	1GPZ 1MD8
Descriptor	C1R COMPLEMENT SERINE PROTEASE, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	complement, innate immunity, serine protease, activation, substrate specificity, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	37275.12
Authors	Budayova-Spano, M.,Grabarse, W.,Thielens, N.M.,Hillen, H.,Lacroix, M.,Schmidt, M.,Fontecilla-Camps, J.,Arlaud, G.J.,Gaboriaud, C. (deposition date: 2002-08-07, release date: 2003-08-07, Last modification date: 2021-11-10)
Primary citation	Budayova-Spano, M.,Grabarse, W.,Thielens, N.M.,Hillen, H.,Lacroix, M.,Schmidt, M.,Fontecilla-Camps, J.,Arlaud, G.J.,Gaboriaud, C. Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10:1509-1519, 2002 Cited by PubMed: 12429092 DOI: 10.1016/S0969-2126(02)00881-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation