1GPZ
THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R
Summary for 1GPZ
Entry DOI | 10.2210/pdb1gpz/pdb |
Related | 1APQ 1ELV |
Descriptor | COMPLEMENT C1R COMPONENT, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | hydrolase, activation, complement, innate immunity, modular structure, serine protease |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 92347.03 |
Authors | Budayova-Spano, M.,Fontecilla-Camps, J.C.,Gaboriaud, C. (deposition date: 2001-11-15, release date: 2002-07-31, Last modification date: 2023-12-13) |
Primary citation | Budayova-Spano, M.,Lacroix, M.,Thielens, N.,Arlaud, G.,Fontecilla-Camps, J.C.,Gaboriaud, C. The Crystal Structure of the Zymogen Catalytic Domain of Complement Protease C1R Reveals that a Disruptive Mechanical Stress is Required to Trigger Activation of the C1 Complex. Embo J., 21:231-, 2002 Cited by PubMed: 11823416DOI: 10.1093/EMBOJ/21.3.231 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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