1GPZ
THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | COMPLEMENT C1R COMPONENT | polymer | 399 | 45411.3 | 2 | UniProt (P00736) Pfam (PF00084) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | C1R COMPLEMENT SERINE PROTEASE |
| 2 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 3 | D (D) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G47477HI) | |||
| 4 | E (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B: 290 - 688 (UniProt: P00736)
| PDB | External Database | Details |
|---|---|---|
| Gln 446 | Arg 463 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90822.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1303.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 92347.0 |
