1MD8

Monomeric structure of the active catalytic domain of complement protease C1r

Summary for 1MD8

Related1gpz 1md7
DescriptorC1R COMPLEMENT SERINE PROTEASE (2 entities in total)
Functional Keywordscomplement, innate immunity, serine protease, activation, substrate specificity, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight37199.03
Authors
Budayova-Spano, M.,Grabarse, W.,Thielens, N.M.,Hillen, H.,Lacroix, M.,Schmidt, M.,Fontecilla-Camps, J.,Arlaud, G.J.,Gaboriaud, C. (deposition date: 2002-08-07, release date: 2003-08-07, Last modification date: 2011-07-13)
Primary citation
Budayova-Spano, M.,Grabarse, W.,Thielens, N.M.,Hillen, H.,Lacroix, M.,Schmidt, M.,Fontecilla-Camps, J.,Arlaud, G.J.,Gaboriaud, C.
Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
Structure, 10:1509-1519, 2002
PubMed: 12429092 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(02)00881-X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.260312.0%6.0%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload