6VRQ

Crystal structure of gl12A21 Fab in complex with anti-idiotypic iv12 Fab

Summary for 6VRQ

Entry DOI	10.2210/pdb6vrq/pdb
Descriptor	iv12 Fab Heavy Chain, iv12 Fab Light Chain, gl12A21 Fab Heavy Chain, ... (9 entities in total)
Functional Keywords	fab, complex, gl12a21, immune system, hiv, cd4-binding site, iv12
Biological source	Mus musculus More
Total number of polymer chains	4
Total formula weight	96639.65
Authors	Aljedani, S.S.,Weidle, C.,Pancera, M. (deposition date: 2020-02-08, release date: 2021-02-17, Last modification date: 2023-10-11)
Primary citation	Seydoux, E.,Wan, Y.H.,Feng, J.,Wall, A.,Aljedani, S.,Homad, L.J.,MacCamy, A.J.,Weidle, C.,Gray, M.D.,Brumage, L.,Taylor, J.J.,Pancera, M.,Stamatatos, L.,McGuire, A.T. Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies. Cell Rep, 35:109084-109084, 2021 Cited by PubMed: 33951425 DOI: 10.1016/j.celrep.2021.109084 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.57 Å)

Structure validation