6WN4

Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase

Summary for 6WN4

• Entry DOI: 10.2210/pdb6wn4/pdb
• Descriptor: 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN, Lipoprotein lipase peptide, ... (4 entities in total)
• Functional Keywords: 5d2, lipoprotein lipase, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 98867.67

Authors

Luz, J.G.,Birrane, G.,Young, S.G.,Meiyappan, M.,Ploug, M. (deposition date: 2020-04-22, release date: 2020-07-29, Last modification date: 2023-10-18)

• Primary citation: Luz, J.G.,Beigneux, A.P.,Asamoto, D.K.,He, C.,Song, W.,Allan, C.M.,Morales, J.,Tu, Y.,Kwok, A.,Cottle, T.,Meiyappan, M.,Fong, L.G.,Kim, J.E.,Ploug, M.,Young, S.G.,Birrane, G.; The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.; J.Lipid Res., 61:1347-1359, 2020; PubMed: 32690595; DOI: 10.1194/jlr.RA120000993

Experimental method

X-RAY DIFFRACTION (2.8 Å)