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7RQP

Structure of PfCSP NPNV binding antibody L9

Summary for 7RQP
Entry DOI10.2210/pdb7rqp/pdb
DescriptorL9 Heavy Chain, L9 Kappa Chain (3 entities in total)
Functional Keywordsmalaria, antibody, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains2
Total formula weight48072.69
Authors
Hurlburt, N.K.,Pancera, M. (deposition date: 2021-08-06, release date: 2022-03-02, Last modification date: 2023-10-18)
Primary citationWang, L.T.,Hurlburt, N.K.,Schon, A.,Flynn, B.J.,Flores-Garcia, Y.,Pereira, L.S.,Kiyuka, P.K.,Dillon, M.,Bonilla, B.,Zavala, F.,Idris, A.H.,Francica, J.R.,Pancera, M.,Seder, R.A.
The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38:110367-110367, 2022
Cited by
PubMed: 35172158
DOI: 10.1016/j.celrep.2022.110367
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.98 Å)
Structure validation

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