1S4D
 
 | | Crystal Structure Analysis of the S-adenosyl-L-methionine dependent uroporphyrinogen-III C-methyltransferase SUMT | | Descriptor: | GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, Uroporphyrin-III C-methyltransferase | | Authors: | Vevodova, J, Graham, R.M, Raux, E, Schubert, H.L, Roper, D.I, Brindley, A.A, Scott, A.I, Roessner, C.A, Stamford, N.P.J, Stroupe, M.E, Getzoff, E.D, Warren, M.J, Wilson, K.S. | | Deposit date: | 2004-01-16 | | Release date: | 2004-11-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure/Function Studies on a S-Adenosyl-l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis
J.Mol.Biol., 344, 2004
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7Q9B
 | | MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | | Deposit date: | 2021-11-12 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.24 Å) | | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
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7Q99
 | | MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR | | Descriptor: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | | Deposit date: | 2021-11-12 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
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7Q98
 | | MHC Class I A02 Allele presenting NLSALGIFST | | Descriptor: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | | Authors: | Rizkallah, P.J, Sewell, A.K. | | Deposit date: | 2021-11-12 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
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7Q9A
 | | MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR | | Descriptor: | Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ... | | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | | Deposit date: | 2021-11-12 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
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7RCO
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1TT6
 | | The orthorhombic crystal structure of transthyretin in complex with diethylstilbestrol | | Descriptor: | DIETHYLSTILBESTROL, GLYCEROL, SULFATE ION, ... | | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | | Deposit date: | 2004-06-22 | | Release date: | 2004-10-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors
J.Biol.Chem., 279, 2004
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1TZ8
 | | The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol | | Descriptor: | ACETATE ION, CARBONATE ION, DIETHYLSTILBESTROL, ... | | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | | Deposit date: | 2004-07-09 | | Release date: | 2004-10-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors
J.Biol.Chem., 279, 2004
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2OG2
 | | Crystal structure of chloroplast FtsY from Arabidopsis thaliana | | Descriptor: | MAGNESIUM ION, MALONATE ION, Putative signal recognition particle receptor | | Authors: | Chartron, J, Chandrasekar, S, Ampornpan, P.J, Shan, S. | | Deposit date: | 2007-01-04 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the Chloroplast Signal Recognition Particle (SRP) Receptor: Domain Arrangement Modulates SRP-Receptor Interaction.
J.Mol.Biol., 375, 2007
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8GVN
 | | Novel salt-resistant antimicrobial peptide, RR14 | | Descriptor: | TRP-LEU-ARG-ARG-ILE-LYS-ALA-TRP-LEU-ARG-ARG-ILE-LYS-ALA | | Authors: | Lin, T.L, Tseng, T.S, Fan, P.J. | | Deposit date: | 2022-09-15 | | Release date: | 2022-11-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Deciphering Structure-Function Relationship Unveils Salt-Resistant Mode of Action of a Potent MRSA-Inhibiting Antimicrobial Peptide, RR14.
J.Bacteriol., 204, 2022
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8TYE
 | | Lassa GPC (strain Josiah) bound to rabbit polyclonal fusion-peptide-targeting antibody FP-1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Perrett, H.R, Brouwer, P.J.M, Ward, A.B. | | Deposit date: | 2023-08-25 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses
To Be Published
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8TYC
 | | Lassa GPC (strain Josiah) bound to rabbit polyclonal base-targeting antibody Base-1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Perrett, H.R, Brouwer, P.J.M, Ward, A.B. | | Deposit date: | 2023-08-24 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Mapping of vaccine-induced humoral responses to the Lassa virus glycoprotein reveals off-target and immunodominant responses
To Be Published
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2OXE
 | | Structure of the Human Pancreatic Lipase-related Protein 2 | | Descriptor: | CALCIUM ION, CHLORIDE ION, Pancreatic lipase-related protein 2, ... | | Authors: | Walker, J.R, Davis, T, Seitova, A, Finerty Jr, P.J, Butler-Cole, C, Kozieradzki, I, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-02-20 | | Release date: | 2007-03-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.
Biochemistry, 47, 2008
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1T31
 | | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S. | | Deposit date: | 2004-04-23 | | Release date: | 2005-03-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
J.Biol.Chem., 280, 2005
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2P0C
 | | Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER | | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-02-28 | | Release date: | 2007-05-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural insights into the inhibited states of the Mer receptor tyrosine kinase.
J.Struct.Biol., 165, 2009
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2F4W
 | | Human ubiquitin-conjugating enzyme E2 J2 | | Descriptor: | ubiquitin-conjugating enzyme E2, J2 | | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Finerty Jr, P.J, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2005-11-24 | | Release date: | 2005-12-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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3O3P
 | | Crystal structure of R. xylanophilus MpgS in complex with GDP-Mannose | | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ... | | Authors: | Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. | | Deposit date: | 2010-07-25 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.529 Å) | | Cite: | Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity
Mol.Microbiol., 79, 2011
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8SDC
 | | Crystal structure of fluoroacetate dehalogenase Daro3835 apoenzyme | | Descriptor: | Alpha/beta hydrolase fold protein, CHLORIDE ION | | Authors: | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | | Deposit date: | 2023-04-06 | | Release date: | 2023-09-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases.
Febs J., 290, 2023
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1WCV
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3U66
 | | Crystal structure of T6SS SciP/TssL from Escherichia Coli Enteroaggregative 042 | | Descriptor: | GLYCEROL, Putative type VI secretion protein | | Authors: | Durand, E, Aschtgen, M.S, Zoued, A, Spinelli, S, Watson, P.J.H, Cambillau, C, Cascales, E. | | Deposit date: | 2011-10-12 | | Release date: | 2012-03-07 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems.
J.Biol.Chem., 287, 2012
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3U8R
 | | Human thrombin complexed with D-Phe-Pro-D-Arg-Ile | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | | Deposit date: | 2011-10-17 | | Release date: | 2012-05-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.
Plos One, 7, 2012
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2BN5
 | | P-Element Somatic Inhibitor Protein Complex with U1-70k proline-rich peptide | | Descriptor: | PSI, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA | | Authors: | Ignjatovic, T, Yang, J.-C, Butler, P.J.G, Neuhaus, D, Nagai, K. | | Deposit date: | 2005-03-21 | | Release date: | 2005-07-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of the Interaction between P-Element Somatic Inhibitor and U1-70K Essential for the Alternative Splicing of P-Element Transposase.
J.Mol.Biol., 351, 2005
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3U8T
 | | Human thrombin complexed with D-Phe-Pro-D-Arg-Cys | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | | Deposit date: | 2011-10-17 | | Release date: | 2012-04-11 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.861 Å) | | Cite: | Rational design and characterization of d-phe-pro-d-arg-derived direct thrombin inhibitors.
Plos One, 7, 2012
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1WYY
 | | Post-fusion hairpin conformation of the sars coronavirus spike glycoprotein | | Descriptor: | CHLORIDE ION, E2 Glycoprotein | | Authors: | Duquerroy, S, Vigouroux, A, Rottier, P.J.M, Rey, F.A, Bosch, B.J. | | Deposit date: | 2005-02-18 | | Release date: | 2005-05-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein
Virology, 335, 2005
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2BN6
 | | P-Element Somatic Inhibitor Protein | | Descriptor: | PSI | | Authors: | Ignjatovic, T, Yang, J.C, Butler, P.J.G, Neuhaus, D, Nagai, K. | | Deposit date: | 2005-03-21 | | Release date: | 2005-07-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of the Interaction between P-Element Somatic Inhibitor and U1-70K Essential for the Alternative Splicing of P-Element Transposase.
J.Mol.Biol., 351, 2005
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