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8TYC

Lassa GPC (strain Josiah) bound to rabbit polyclonal base-targeting antibody Base-1

Summary for 8TYC
Entry DOI10.2210/pdb8tyc/pdb
EMDB information41713
DescriptorGlycoprotein G1, 2-acetamido-2-deoxy-beta-D-glucopyranose, Polyclonal antibody Base-1 heavy chain, ... (10 entities in total)
Functional Keywordslassa virus glycoprotein complex, gpc, immune complex, antibody, polyclonal antibody, base antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceLassa virus
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Total number of polymer chains8
Total formula weight255615.62
Authors
Perrett, H.R.,Brouwer, P.J.M.,Ward, A.B. (deposition date: 2023-08-24, release date: 2024-09-11)
Primary citationBrouwer, P.J.M.,Perrett, H.R.,Nijhuis, H.,Lee, W.-H.,Burger, J.,Lloyd, N.M.,Himansu, S.,Beaumont, T.,Carfi, A.,Bukreyev, A.,Sanders, R.W.,van Gils, M.J.,Ward, A.B.
Mapping of vaccine-induced humoral responses to the Lassa virus glycoprotein reveals off-target and immunodominant responses
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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PDB entries from 2024-09-11

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