8TYE
Lassa GPC (strain Josiah) bound to rabbit polyclonal fusion-peptide-targeting antibody FP-1
Summary for 8TYE
Entry DOI | 10.2210/pdb8tye/pdb |
EMDB information | 41715 |
Descriptor | Polyclonal Fv heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, Polyclonal Fv light chain, ... (10 entities in total) |
Functional Keywords | lassa virus glycoprotein complex, gpc, immune complex, antibody, polyclonal antibody, base antibody, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) More |
Total number of polymer chains | 8 |
Total formula weight | 252445.84 |
Authors | Perrett, H.R.,Brouwer, P.J.M.,Ward, A.B. (deposition date: 2023-08-25, release date: 2024-09-11, Last modification date: 2024-09-25) |
Primary citation | Brouwer, P.J.M.,Perrett, H.R.,Beaumont, T.,Nijhuis, H.,Kruijer, S.,Burger, J.A.,Bontjer, I.,Lee, W.H.,Ferguson, J.A.,Schauflinger, M.,Muller-Krauter, H.,Sanders, R.W.,Strecker, T.,van Gils, M.J.,Ward, A.B. Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses. Cell Rep, 43:114708-114708, 2024 Cited by PubMed: 39243373DOI: 10.1016/j.celrep.2024.114708 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report