8TYE
Lassa GPC (strain Josiah) bound to rabbit polyclonal fusion-peptide-targeting antibody FP-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Polyclonal Fv heavy chain | polymer | 116 | 9890.2 | 1 | Oryctolagus cuniculus (rabbit) | ||
| 2 | B (L) | Polyclonal Fv light chain | polymer | 102 | 8698.7 | 1 | Oryctolagus cuniculus (rabbit) | ||
| 3 | C, D, E (C, A, B) | Glycoprotein GP1 | polymer | 259 | 29010.4 | 3 | UniProt (P08669) Pfam (PF00798) | Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) | |
| 4 | F, G, H (c, a, b) | Glycoprotein GP2 | polymer | 406 | 44765.0 | 3 | UniProt (P08669) UniProt (Q9WXS1) Pfam (PF00798) Pfam (PF01081) | Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) | GP2 |
| 5 | I (D) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 6 | J, X (E, U) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G22573RC) | |||
| 7 | K, O (F, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 8 | AA, L, M, N, P... (X, G, I, J, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 11 | In PDB GlyTouCan (G42666HT) | |||
| 9 | V, W, Z (S, T, W) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 10 | BA, CA, DA, EA, FA... (C, A, B, c, a...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 14 | Chemie (NAG) |
Sequence modifications
C, A, B: 1 - 259 (UniProt: P08669)
c, a, b: 260 - 424 (UniProt: P08669)
c, a, b: 450 - 653 (UniProt: Q9WXS1)
| PDB | External Database | Details |
|---|---|---|
| Cys 207 | Arg 207 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Pro 329 | Glu 329 | conflict |
| Cys 360 | Gly 360 | conflict |
| Gly 425 | - | linker |
| Ser 426 | - | linker |
| Gly 427 | - | linker |
| Gly 428 | - | linker |
| Ser 429 | - | linker |
| Gly 430 | - | linker |
| Gly 431 | - | linker |
| Ser 432 | - | linker |
| Gly 433 | - | linker |
| Gly 434 | - | linker |
| Ser 435 | - | linker |
| Gly 436 | - | linker |
| Gly 437 | - | linker |
| Ser 438 | - | linker |
| Glu 439 | - | linker |
| Lys 440 | - | linker |
| Ala 441 | - | linker |
| Ala 442 | - | linker |
| Lys 443 | - | linker |
| Ala 444 | - | linker |
| Glu 445 | - | linker |
| Glu 446 | - | linker |
| Ala 447 | - | linker |
| Ala 448 | - | linker |
| Arg 449 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ile 473 | Lys 25 | conflict |
| Val 477 | Leu 29 | conflict |
| Ala 481 | Glu 33 | conflict |
| Ala 502 | Glu 54 | conflict |
| Val 505 | Phe 57 | conflict |
| Asp 574 | Thr 126 | conflict |
| Glu 587 | Gln 139 | conflict |
| Asp 608 | Asn 160 | conflict |
| Asp 617 | Lys 169 | conflict |
| Asp 627 | Ser 179 | conflict |
| Glu 631 | Lys 183 | conflict |
| Asp 633 | Thr 185 | conflict |
| Glu 643 | Ala 195 | conflict |
| Gly 654 | - | expression tag |
| Ser 655 | - | expression tag |
| Leu 656 | - | expression tag |
| Glu 657 | - | expression tag |
| Trp 658 | - | expression tag |
| Ser 659 | - | expression tag |
| His 660 | - | expression tag |
| Pro 661 | - | expression tag |
| Gln 662 | - | expression tag |
| Phe 663 | - | expression tag |
| Glu 664 | - | expression tag |
| Lys 665 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 239915.1 | |
| Branched | Number of molecules | 19 |
| Total formula weight | 9433.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3096.9 | |
| All* | Total formula weight | 252445.8 |
