7Q9B
MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR
This is a non-PDB format compatible entry.
Summary for 7Q9B
Entry DOI | 10.2210/pdb7q9b/pdb |
Descriptor | MHC class I antigen, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... (7 entities in total) |
Functional Keywords | melanoma epitope, autoimmunity, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 187425.63 |
Authors | Rizkallah, P.J.,Sewell, A.K.,Wall, A.,Fuller, A. (deposition date: 2021-11-12, release date: 2023-02-22, Last modification date: 2024-02-07) |
Primary citation | Dolton, G.,Rius, C.,Wall, A.,Szomolay, B.,Bianchi, V.,Galloway, S.A.E.,Hasan, M.S.,Morin, T.,Caillaud, M.E.,Thomas, H.L.,Theaker, S.,Tan, L.R.,Fuller, A.,Topley, K.,Legut, M.,Attaf, M.,Hopkins, J.R.,Behiry, E.,Zabkiewicz, J.,Alvares, C.,Lloyd, A.,Rogers, A.,Henley, P.,Fegan, C.,Ottmann, O.,Man, S.,Crowther, M.D.,Donia, M.,Svane, I.M.,Cole, D.K.,Brown, P.E.,Rizkallah, P.,Sewell, A.K. Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186:3333-3349.e27, 2023 Cited by PubMed: 37490916DOI: 10.1016/j.cell.2023.06.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.24 Å) |
Structure validation
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