7LYT
| Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA and Phosphorothioate-DNA | 分子名称: | CasPhi, MAGNESIUM ION, NTS-DNA*, ... | 著者 | Pausch, P, Soczek, K, Nogales, E, Doudna, J. | 登録日 | 2021-03-08 | 公開日 | 2021-08-04 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | DNA interference states of the hypercompact CRISPR-Cas Phi effector. Nat.Struct.Mol.Biol., 28, 2021
|
|
5M33
| Structural tuning of CD81LEL (space group P21) | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | 登録日 | 2016-10-14 | 公開日 | 2016-12-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop. Structure, 25, 2017
|
|
5M3T
| Structural tuning of CD81LEL (space group P64) | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen, CHLORIDE ION | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | 登録日 | 2016-10-17 | 公開日 | 2016-12-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.021 Å) | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop. Structure, 25, 2017
|
|
5M4B
| Alpha-amino epsilon-caprolactam racemase D210A mutant in complex with PLP and geminal diamine intermediate | 分子名称: | 1,2-ETHANEDIOL, Aminotransferase class-III, [6-methyl-5-oxidanyl-4-[(~{E})-[(3~{R})-2-oxidanylideneazepan-3-yl]iminomethyl]pyridin-3-yl]methyl dihydrogen phosphate | 著者 | Frese, A, Sutton, P.W, Turkenburg, J.P, Grogan, G. | 登録日 | 2016-10-18 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Snapshots of the Catalytic Cycle of the Industrial Enzyme alpha-Amino-epsilon-Caprolactam Racemase (ACLR) Observed Using X-ray Crystallography Acs Catalysis, 7, 2017
|
|
7T8S
| Light Harvesting complex phycoerythrin PE 566, from the cryptophyte Cryptomonas pyrenoidifera | 分子名称: | Bilin 584 (doubly linked), Bilin 584 (single linked), Bilin 618 (single linked), ... | 著者 | Michie, K.A, Harrop, S.J, Rathbone, H.W, Wilk, K.E, Curmi, P.M.G. | 登録日 | 2021-12-17 | 公開日 | 2023-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular structures reveal the origin of spectral variation in cryptophyte light harvesting antenna proteins. Protein Sci., 32, 2023
|
|
7OVW
| Binding domain of botulinum neurotoxin E in complex with GD1a | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Neurotoxin type E | 著者 | Masuyer, G, Stenmark, P. | 登録日 | 2021-06-15 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E. Int J Mol Sci, 22, 2021
|
|
4QIO
| Lambda-[Ru(TAP)2(dppz)]2+ bound to d(TCGGCGCCIA) at high resolution | 分子名称: | 5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*IP*A)-3', BARIUM ION, CHLORIDE ION, ... | 著者 | Gurung, S.P, Hall, J.P, Cardin, C.J. | 登録日 | 2014-06-01 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Inosine Can Increase DNA's Susceptibility to Photo-oxidation by a Ru II Complex due to Structural Change in the Minor Groove. Chemistry, 23, 2017
|
|
6U1X
| Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor (3.0 A resolution) | 分子名称: | Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION | 著者 | Jenni, S, Bloyet, L.M, Dias-Avalos, R, Liang, B, Wheelman, S.P.J, Grigorieff, N, Harrison, S.C. | 登録日 | 2019-08-17 | 公開日 | 2020-01-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor. Cell Rep, 30, 2020
|
|
5M49
| Alpha-amino epsilon-caprolactam racemase in complex with PLP and D/L alpha amino epsilon-caprolactam (internal aldimine) | 分子名称: | (3~{R})-3-azanylazepan-2-one, (3~{S})-3-azanylazepan-2-one, Aminotransferase class-III, ... | 著者 | Frese, A, Sutton, P.W, Turkenburg, J.P, Grogan, G. | 登録日 | 2016-10-18 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Snapshots of the Catalytic Cycle of the Industrial Enzyme alpha-Amino-epsilon-Caprolactam Racemase (ACLR) Observed Using X-ray Crystallography Acs Catalysis, 7, 2017
|
|
7LZE
| Cryo-EM Structure of disulfide stabilized HMPV F v4-B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 | 著者 | Gorman, J, Kwong, P.D. | 登録日 | 2021-03-09 | 公開日 | 2021-08-25 | 最終更新日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8CXL
| Structure of NapH3, a vanadium-dependent haloperoxidase homolog catalyzing the stereospecific alpha-hydroxyketone rearrangement reaction in napyradiomycin biosynthesis | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NapH3 | 著者 | Chen, P.Y.-T, Chekan, J.R, Moore, B.S. | 登録日 | 2022-05-21 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis. Biochemistry, 61, 2022
|
|
5J7A
| Bacteriorhodopsin ground state structure obtained with Serial Femtosecond Crystallography | 分子名称: | 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, RETINAL | 著者 | Nogly, P, Panneels, V, Nelson, G, Gati, C, Kimura, T, Milne, C, Milathianaki, D, Kubo, M, Wu, W, Conrad, C, Coe, J, Bean, R, Zhao, Y, Bath, P, Dods, R, Harimoorthy, R, Beyerlein, K.R, Rheinberger, J, James, D, DePonte, D, Li, C, Sala, L, Williams, G, Hunter, M, Koglin, J.E, Berntsen, P, Nango, E, Iwata, S, Chapman, H.N, Fromme, P, Frank, M, Abela, R, Boutet, S, Barty, A, White, T.A, Weierstall, U, Spence, J, Neutze, R, Schertler, G, Standfuss, J. | 登録日 | 2016-04-06 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography. Nat Commun, 7, 2016
|
|
5LV6
| N-terminal motif dimerization of EGFR transmembrane domain in bicellar environment | 分子名称: | Epidermal growth factor receptor | 著者 | Bragin, P, Bocharov, E, Mineev, K, Bocharova, O, Arseniev, A. | 登録日 | 2016-09-12 | 公開日 | 2017-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane Environment. Biochemistry, 56, 2017
|
|
6ZFU
| Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor RKA066 | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Amporndanai, K, O'Neill, P.M, Hong, W.D, Amewu, R.K, Pidathala, C, Berry, N.G, Biagini, G.A, Leung, S.C, Hasnain, S.S, Antonyuk, S.V. | 登録日 | 2020-06-17 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials To Be Published
|
|
6ZFS
| Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor WDH-1U-4 | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Amporndanai, K, O'Neill, P.M, Hong, W.D, Amewu, R.K, Pidathala, C, Berry, N.G, Biagini, G.A, Leung, S.C, Hasnain, S.S, Antonyuk, S.V. | 登録日 | 2020-06-17 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials To Be Published
|
|
6Z9V
| Human Class I Major Histocompatibility Complex, A02 allele, presenting IIGWMWIPV | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | 著者 | Rizkallah, P.J, Man, S, Redman, J.E. | 登録日 | 2020-06-04 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells. J Immunol., 207, 2021
|
|
6ZFT
| Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor CK-2-68 | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Amporndanai, K, O'Neill, P.M, Hong, W.D, Amewu, R.K, Pidathala, C, Berry, N.G, Biagini, G.A, Leung, S.C, Hasnain, S.S, Antonyuk, S.V. | 登録日 | 2020-06-17 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials To Be Published
|
|
7ZUS
| Crystal structure of ternary complex of Pol theta polymerase domain | 分子名称: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*(DDG))-3'), DNA (5'-D(P*TP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*C)-3'), ... | 著者 | Krajewski, W.W, Turnbull, A.P, Willis, S, Charles, M, Stockley, M, Heald, R.A. | 登録日 | 2022-05-13 | 公開日 | 2022-10-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta. J.Med.Chem., 65, 2022
|
|
6WKN
| PL-bound rat TRPV2 in nanodiscs | 分子名称: | Transient receptor potential cation channel subfamily V member 2, piperlongumine | 著者 | Pumroy, R.P, Moiseenkova-Bell, V.Y. | 登録日 | 2020-04-16 | 公開日 | 2021-04-21 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression. Acs Cent.Sci., 7, 2021
|
|
6WKV
| Cryo-EM structure of engineered variant of the Encapsulin from Thermotoga maritima (TmE) | 分子名称: | Encapsulin, FLAVIN MONONUCLEOTIDE | 著者 | Williams, E, Jenkins, M, Zhao, H, Juneja, P, Lutz, S. | 登録日 | 2020-04-17 | 公開日 | 2021-04-21 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Cryo-EM structure of engineered variant of the Encapsulin from Thermotoga maritima (TmE) To Be Published
|
|
8FBC
| Crystal structure of P450T2 | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Pereira, J.H, Huang, J, Keasling, J, Adams, P.D. | 登録日 | 2022-11-29 | 公開日 | 2023-05-10 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Complete integration of carbene-transfer chemistry into biosynthesis. Nature, 617, 2023
|
|
8TH6
| Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide | 分子名称: | 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10 | 著者 | Hughes, M.P, Taylor, J.P, Yang, Z. | 登録日 | 2023-07-14 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity. Cell Rep, 43, 2024
|
|
7ZHH
| Complex structure of drosophila Unr CSD789 and a poly(A) RNA sequence | 分子名称: | RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION, Upstream of N-ras, ... | 著者 | Hollmann, N.M, Jagtap, P.K.A, Hennig, J. | 登録日 | 2022-04-06 | 公開日 | 2022-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Upstream of N-Ras C-terminal cold shock domains mediate poly(A) specificity in a novel RNA recognition mode and bind poly(A) binding protein. Nucleic Acids Res., 51, 2023
|
|
8TH5
| |
6OW2
| X-ray Structure of Polypeptide Deformylase | 分子名称: | (2R)-2-(cyclopentylmethyl)-N'-{5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-methylpyrimidin-4-yl}-3-[hydroxy(hydroxymethyl)amino]propanehydrazide, NICKEL (II) ION, Peptide deformylase | 著者 | Campobasso, N, Spletstoser, J, Ward, P. | 登録日 | 2019-05-09 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections. Bioorg.Med.Chem.Lett., 29, 2019
|
|