7OVW

Binding domain of botulinum neurotoxin E in complex with GD1a

This is a non-PDB format compatible entry.

Summary for 7OVW

• Entry DOI: 10.2210/pdb7ovw/pdb
• Descriptor: Neurotoxin type E, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... (4 entities in total)
• Functional Keywords: botulinum neurotoxin, ganglioside, toxin receptor, bacterial toxin, carbohydrate binding, toxin
• Biological source: Clostridium botulinum
• Total number of polymer chains: 2
• Total formula weight: 110494.68

Authors

Masuyer, G.,Stenmark, P. (deposition date: 2021-06-15, release date: 2021-08-11, Last modification date: 2024-01-31)

• Primary citation: Masuyer, G.,Davies, J.R.,Stenmark, P.; Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E.; Int J Mol Sci, 22:-, 2021; PubMed: 34361086; DOI: 10.3390/ijms22158315

Experimental method

X-RAY DIFFRACTION (2.2 Å)