Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5LV6

N-terminal motif dimerization of EGFR transmembrane domain in bicellar environment

Summary for 5LV6
Entry DOI10.2210/pdb5lv6/pdb
NMR InformationBMRB: 34040
DescriptorEpidermal growth factor receptor (1 entity in total)
Functional Keywordsepidermal growth factor receptor, bicelles, activation mechanism, transferase
Biological sourceHomo sapiens (Human)
Cellular locationCell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533
Total number of polymer chains2
Total formula weight9467.70
Authors
Bragin, P.,Bocharov, E.,Mineev, K.,Bocharova, O.,Arseniev, A. (deposition date: 2016-09-12, release date: 2017-04-05, Last modification date: 2023-06-14)
Primary citationBocharov, E.V.,Bragin, P.E.,Pavlov, K.V.,Bocharova, O.V.,Mineev, K.S.,Polyansky, A.A.,Volynsky, P.E.,Efremov, R.G.,Arseniev, A.S.
The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane Environment.
Biochemistry, 56:1697-1705, 2017
Cited by
PubMed: 28291355
DOI: 10.1021/acs.biochem.6b01085
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon