5NOI
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2HT6
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1T3S
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![BU of 1t3s by Molmil](/molmil-images/mine/1t3s) | Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core | Descriptor: | Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, MERCURY (II) ION | Authors: | Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A. | Deposit date: | 2004-04-27 | Release date: | 2004-05-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain. Neuron, 42, 2004
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1T3L
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![BU of 1t3l by Molmil](/molmil-images/mine/1t3l) | Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core in Complex with Alpha1 Interaction Domain | Descriptor: | Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, Voltage-dependent L-type calcium channel alpha-1S subunit | Authors: | Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A. | Deposit date: | 2004-04-27 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Analysis of Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain NEURON, 42, 2004
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4RTT
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4RUG
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4PQJ
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6QWV
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![BU of 6qwv by Molmil](/molmil-images/mine/6qwv) | SARM1 SAM1-2 domains | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sporny, M, Isupov, N.M, Opatowsky, Y. | Deposit date: | 2019-03-06 | Release date: | 2019-07-03 | Last modified: | 2019-09-18 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural Evidence for an Octameric Ring Arrangement of SARM1. J.Mol.Biol., 431, 2019
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8P2M
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![BU of 8p2m by Molmil](/molmil-images/mine/8p2m) | C. elegans TIR-1 protein. | Descriptor: | NAD(+) hydrolase tir-1 | Authors: | Isupov, M.N, Opatowsky, Y. | Deposit date: | 2023-05-16 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans. Cell Rep, 42, 2023
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8P2L
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7ANW
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![BU of 7anw by Molmil](/molmil-images/mine/7anw) | hSARM1 NAD+ complex | Descriptor: | NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Mim, C, Isupov, M.N, Zalk, R, Dessau, M, Hons, M, Opatowsky, Y. | Deposit date: | 2020-10-13 | Release date: | 2020-11-11 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Structural basis for SARM1 inhibition and activation under energetic stress. Elife, 9, 2020
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3KVQ
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4HLJ
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![BU of 4hlj by Molmil](/molmil-images/mine/4hlj) | Axon Guidance Receptor | Descriptor: | PENTAETHYLENE GLYCOL, Roundabout homolog 1 | Authors: | Barak, R, Opatowsky, Y. | Deposit date: | 2012-10-17 | Release date: | 2013-11-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Axon Guidance Receptor To be Published
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6ZG0
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![BU of 6zg0 by Molmil](/molmil-images/mine/6zg0) | SARM1 SAM1-2 domains | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | Deposit date: | 2020-06-18 | Release date: | 2020-11-11 | Last modified: | 2020-12-09 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Structural basis for SARM1 inhibition and activation under energetic stress. Elife, 9, 2020
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6ZFX
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![BU of 6zfx by Molmil](/molmil-images/mine/6zfx) | hSARM1 GraFix-ed | Descriptor: | (~{E})-4-methylnon-4-enedial, NAD(+) hydrolase SARM1 | Authors: | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | Deposit date: | 2020-06-18 | Release date: | 2020-11-18 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural basis for SARM1 inhibition and activation under energetic stress. Elife, 9, 2020
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6ZG1
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![BU of 6zg1 by Molmil](/molmil-images/mine/6zg1) | SARM1 SAM1-2 domains | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | Deposit date: | 2020-06-18 | Release date: | 2020-11-11 | Last modified: | 2020-12-09 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural basis for SARM1 inhibition and activation under energetic stress. Elife, 9, 2020
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5I6J
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5I7D
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5I6R
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![BU of 5i6r by Molmil](/molmil-images/mine/5i6r) | Crystal Structure of srGAP2 F-BARx WT Form-1 | Descriptor: | ACETATE ION, D-MALATE, SLIT-ROBO Rho GTPase-activating protein 2, ... | Authors: | Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y. | Deposit date: | 2016-02-16 | Release date: | 2017-08-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C To Be Published
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2EC8
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![BU of 2ec8 by Molmil](/molmil-images/mine/2ec8) | Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor | Authors: | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | Deposit date: | 2007-02-11 | Release date: | 2007-08-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor Cell(Cambridge,Mass.), 130, 2007
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2E9W
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![BU of 2e9w by Molmil](/molmil-images/mine/2e9w) | Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor | Authors: | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | Deposit date: | 2007-01-27 | Release date: | 2007-08-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor Cell(Cambridge,Mass.), 130, 2007
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6I9S
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6IAA
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![BU of 6iaa by Molmil](/molmil-images/mine/6iaa) | hRobo2 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Barak, R, Isupov, N.M, Opatowsky, Y. | Deposit date: | 2018-11-26 | Release date: | 2019-03-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural Principles in Robo Activation and Auto-inhibition. Cell, 177, 2019
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4OMB
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![BU of 4omb by Molmil](/molmil-images/mine/4omb) | Phosphate binding protein | Descriptor: | PHOSPHATE ION, PLATINUM (II) ION, Phosphate binding protein | Authors: | Neznansky, A, Opatowsky, Y. | Deposit date: | 2014-01-27 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Pseudomonas aeruginosa phosphate transport protein PstS plays a phosphate-independent role in biofilm formation. Faseb J., 28, 2014
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