Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment

Summary for 4RUG

DescriptorSLIT-ROBO Rho GTPase-activating protein 2 (2 entities in total)
Functional Keywordssrgap2, sh3, ligand binding, robo1, nuclear, plasma membrane, protein binding
Biological sourceHomo sapiens (human)
Cellular locationCell membrane O75044
Total number of polymer chains2
Total molecular weight20542.8
Opatowsky, Y.,Guez-Hadad, J. (deposition date: 2014-11-19, release date: 2015-11-04, Last modification date: 2017-11-22)
Primary citation
Guez-Haddad, J.,Sporny, M.,Sasson, Y.,Gevorkyan-Airapetov, L.,Lahav-Mankovski, N.,Margulies, D.,Radzimanowski, J.,Opatowsky, Y.
The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23:1989-2000, 2015
PubMed: 26365803 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2015.08.009
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23121.2%1.4%4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report