1T3L

Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core in Complex with Alpha1 Interaction Domain

Summary for 1T3L

Related1t3s
DescriptorDihydropyridine-sensitive L-type, calcium channel beta-2 subunit, Voltage-dependent L-type calcium channel alpha-1S subunit (3 entities in total)
Functional Keywordsprotein-peptide complex, sh3 domain, guanylate kinase domain, transport protein
Biological sourceOryctolagus cuniculus (rabbit)
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Cellular locationCell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side (By similarity) P54288
Membrane; Multi-pass membrane protein P07293
Total number of polymer chains2
Total molecular weight40525.32
Authors
Opatowsky, Y.,Chen, C.-C.,Campbell, K.P.,Hirsch, J.A. (deposition date: 2004-04-27, release date: 2004-05-25, Last modification date: 2011-07-13)
Primary citation
Opatowsky, Y.,Chen, C.-C.,Campbell, K.P.,Hirsch, J.A.
Structural Analysis of Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain
NEURON, 42:387-399, 2004
PubMed: 15134636 (PDB entries with the same primary citation)
DOI: 10.1016/S0896-6273(04)00250-8
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers122.5%7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution