1T3L
Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core in Complex with Alpha1 Interaction Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit | polymer | 337 | 38341.0 | 1 | UniProt (P54288) Pfam (PF12052) Pfam (PF00625) | Oryctolagus cuniculus (rabbit) | Voltage-Dependent Calcium Channel Beta-2 Subunit, CAB2 |
| 2 | B (B) | Voltage-dependent L-type calcium channel alpha-1S subunit | polymer | 18 | 2184.4 | 1 | UniProt (P07293) | Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle | |
| 3 | C, D (A, B) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 25 - 422 (UniProt: P54288)
| PDB | External Database | Details |
|---|---|---|
| Arg 122 | Pro 122 | engineered mutation |
| Glu 138 | - | SEE REMARK 999 |
| Phe 139 | - | SEE REMARK 999 |
| Lys 140 | - | SEE REMARK 999 |
| Leu 141 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40525.3 | |
| All* | Total formula weight | 40525.3 |
