3KVQ
Crystal structure of VEGFR2 extracellular domain D7
Summary for 3KVQ
Entry DOI | 10.2210/pdb3kvq/pdb |
Descriptor | Vascular endothelial growth factor receptor 2 (2 entities in total) |
Functional Keywords | vegfr2, angiogenesis, atp-binding, developmental protein, differentiation, glycoprotein, host-virus interaction, immunoglobulin domain, kinase, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, transferase, transmembrane, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P35968 |
Total number of polymer chains | 1 |
Total formula weight | 11912.40 |
Authors | Yang, Y.,Opatowsky, Y.,Xie, P.,Schlessinger, J. (deposition date: 2009-11-30, release date: 2010-02-16, Last modification date: 2023-09-06) |
Primary citation | Yang, Y.,Xie, P.,Opatowsky, Y.,Schlessinger, J. Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling Proc.Natl.Acad.Sci.USA, 107:1906-1911, 2010 Cited by PubMed: 20080685DOI: 10.1073/pnas.0914052107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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