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PDB: 24 件

4PQJ
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Crystal structure of a phosphate binding protein
分子名称: PHOSPHATE ION, Phosphate binding protein
著者Opatowsky, Y, Neznansky, A.
登録日2014-03-03
公開日2015-03-18
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structure of a phosphate binding protein
TO BE PUBLISHED
2HT6
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Crystal structure of Human Gem G-domain bound to GDP
分子名称: GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Opatowsky, Y, Hirsch, J.A.
登録日2006-07-25
公開日2006-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-function studies of the G-domain from human gem, a novel small G-protein.
Febs Lett., 580, 2006
5NOI
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BU of 5noi by Molmil
human Robo2 extracellular domains 4-5
分子名称: Roundabout homolog 2
著者Opatowsky, Y, Barak, R.
登録日2017-04-12
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Robo Ig4 Is a Dimerization Domain.
J. Mol. Biol., 429, 2017
4RTT
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Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment
分子名称: SLIT-ROBO Rho GTPase-activating protein 2, SULFATE ION
著者Opatowsky, Y, Guez-Hadad, J.
登録日2014-11-16
公開日2015-11-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23, 2015
4RUG
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BU of 4rug by Molmil
Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment
分子名称: SLIT-ROBO Rho GTPase-activating protein 2
著者Opatowsky, Y, Guez-Hadad, J.
登録日2014-11-19
公開日2015-11-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23, 2015
1T3S
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BU of 1t3s by Molmil
Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core
分子名称: Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, MERCURY (II) ION
著者Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A.
登録日2004-04-27
公開日2004-05-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain.
Neuron, 42, 2004
1T3L
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BU of 1t3l by Molmil
Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core in Complex with Alpha1 Interaction Domain
分子名称: Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, Voltage-dependent L-type calcium channel alpha-1S subunit
著者Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A.
登録日2004-04-27
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain
NEURON, 42, 2004
3KVQ
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BU of 3kvq by Molmil
Crystal structure of VEGFR2 extracellular domain D7
分子名称: Vascular endothelial growth factor receptor 2
著者Yang, Y, Opatowsky, Y, Xie, P, Schlessinger, J.
登録日2009-11-30
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Proc.Natl.Acad.Sci.USA, 107, 2010
5I6J
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BU of 5i6j by Molmil
Crystal Structure of SRGAP2 F-BARx
分子名称: SLIT-ROBO Rho GTPase-activating protein 2
著者Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
登録日2016-02-16
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural History of Human SRGAP2 Proteins.
Mol. Biol. Evol., 34, 2017
5I7D
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Crystal Structure of srGAP2 F-BARx WT Form-2
分子名称: SLIT-ROBO Rho GTPase-activating protein 2
著者Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
登録日2016-02-17
公開日2017-08-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C
To Be Published
6QWV
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BU of 6qwv by Molmil
SARM1 SAM1-2 domains
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Sporny, M, Isupov, N.M, Opatowsky, Y.
登録日2019-03-06
公開日2019-07-03
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural Evidence for an Octameric Ring Arrangement of SARM1.
J.Mol.Biol., 431, 2019
5I6R
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BU of 5i6r by Molmil
Crystal Structure of srGAP2 F-BARx WT Form-1
分子名称: ACETATE ION, D-MALATE, SLIT-ROBO Rho GTPase-activating protein 2, ...
著者Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
登録日2016-02-16
公開日2017-08-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C
To Be Published
7ANW
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hSARM1 NAD+ complex
分子名称: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Mim, C, Isupov, M.N, Zalk, R, Dessau, M, Hons, M, Opatowsky, Y.
登録日2020-10-13
公開日2020-11-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6ZFX
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hSARM1 GraFix-ed
分子名称: (~{E})-4-methylnon-4-enedial, NAD(+) hydrolase SARM1
著者Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
登録日2020-06-18
公開日2020-11-18
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6ZG1
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BU of 6zg1 by Molmil
SARM1 SAM1-2 domains
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
登録日2020-06-18
公開日2020-11-11
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6ZG0
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BU of 6zg0 by Molmil
SARM1 SAM1-2 domains
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
登録日2020-06-18
公開日2020-11-11
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
4HLJ
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BU of 4hlj by Molmil
Axon Guidance Receptor
分子名称: PENTAETHYLENE GLYCOL, Roundabout homolog 1
著者Barak, R, Opatowsky, Y.
登録日2012-10-17
公開日2013-11-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Axon Guidance Receptor
To be Published
4OMB
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BU of 4omb by Molmil
Phosphate binding protein
分子名称: PHOSPHATE ION, PLATINUM (II) ION, Phosphate binding protein
著者Neznansky, A, Opatowsky, Y.
登録日2014-01-27
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Pseudomonas aeruginosa phosphate transport protein PstS plays a phosphate-independent role in biofilm formation.
Faseb J., 28, 2014
8P2M
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BU of 8p2m by Molmil
C. elegans TIR-1 protein.
分子名称: NAD(+) hydrolase tir-1
著者Isupov, M.N, Opatowsky, Y.
登録日2023-05-16
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8P2L
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BU of 8p2l by Molmil
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
分子名称: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Isupov, M.N, Opatowsky, Y.
登録日2023-05-16
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
2EC8
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BU of 2ec8 by Molmil
Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor
著者Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2007-02-11
公開日2007-08-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
2E9W
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Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor
著者Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2007-01-27
公開日2007-08-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
6I9S
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BU of 6i9s by Molmil
hRobo2 Extracellular Domains 2-3
分子名称: Roundabout homolog 2, SODIUM ION
著者Barak, R, Isupov, N.M, Opatowsky, Y.
登録日2018-11-25
公開日2019-03-13
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
6IAA
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hRobo2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Barak, R, Isupov, N.M, Opatowsky, Y.
登録日2018-11-26
公開日2019-03-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019

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件を2024-07-17に公開中

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