1VOK
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8GH4
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![BU of 8gh4 by Molmil](/molmil-images/mine/8gh4) | Complex of Adam 10 disentegrin cysteine rich domains with human monoclonal antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ... | 著者 | Nikolov, D.B, Saha, N, Xu, K, Goldgur, Y. | 登録日 | 2023-03-09 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells. Biomed Pharmacother, 161, 2023
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1VOL
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![BU of 1vol by Molmil](/molmil-images/mine/1vol) | TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX | 分子名称: | DNA (5'-D(*CP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ... | 著者 | Nikolov, D.B, Chen, H, Halay, E.D, Usheva, A.U, Hisatake, K, Lee, D.K, Roeder, R.G, Burley, S.K. | 登録日 | 1996-04-29 | 公開日 | 1996-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature, 377, 1995
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1CDW
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![BU of 1cdw by Molmil](/molmil-images/mine/1cdw) | HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA | 分子名称: | DNA (5'-D(*CP*AP*GP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)) | 著者 | Nikolov, D.B, Chen, H, Halay, E.D, Hoffmann, A, Roeder, R.G, Burley, S.K. | 登録日 | 1996-04-11 | 公開日 | 1996-12-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a human TATA box-binding protein/TATA element complex. Proc.Natl.Acad.Sci.USA, 93, 1996
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7S7K
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![BU of 7s7k by Molmil](/molmil-images/mine/7s7k) | Crystal structure of the EphB2 extracellular domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ... | 著者 | Xu, Y, Xu, K, Nikolov, D.B. | 登録日 | 2021-09-16 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism. Int J Mol Sci, 22, 2021
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1VTL
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5EVM
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5L0Q
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![BU of 5l0q by Molmil](/molmil-images/mine/5l0q) | Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ... | 著者 | Xu, K, Saha, N, Nikolov, D.B. | 登録日 | 2016-07-28 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.759 Å) | 主引用文献 | An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth. J.Exp.Med., 213, 2016
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1MP5
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![BU of 1mp5 by Molmil](/molmil-images/mine/1mp5) | Y177F VARIANT OF S. ENTERICA RmlA | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE | 著者 | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | 登録日 | 2002-09-11 | 公開日 | 2002-10-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering Proc.Natl.Acad.Sci.USA, 99, 2002
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1MP4
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![BU of 1mp4 by Molmil](/molmil-images/mine/1mp4) | W224H VARIANT OF S. ENTERICA RmlA | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, W224H Variant of S. Enterica RmlA Bound to UDP-Glucose | 著者 | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | 登録日 | 2002-09-11 | 公開日 | 2002-10-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering Proc.Natl.Acad.Sci.USA, 99, 2002
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2AO7
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![BU of 2ao7 by Molmil](/molmil-images/mine/2ao7) | Adam10 Disintegrin and cysteine- rich domain | 分子名称: | ADAM 10, SULFATE ION | 著者 | Janes, P.W, Saha, N, Barton, W.A, Kolev, M.V, Wimmer-Kleikamp, S.H, Nievergall, E, Blobel, C.P, Himanen, J.-P, Lackmann, M, Nikolov, D.B. | 登録日 | 2005-08-12 | 公開日 | 2006-08-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell(Cambridge,Mass.), 123, 2005
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2GY5
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![BU of 2gy5 by Molmil](/molmil-images/mine/2gy5) | Tie2 Ligand-Binding Domain Crystal Structure | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ... | 著者 | Barton, W.A, Nikolov, D.B. | 登録日 | 2006-05-09 | 公開日 | 2006-06-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex. Nat.Struct.Mol.Biol., 13, 2006
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2GY7
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![BU of 2gy7 by Molmil](/molmil-images/mine/2gy7) | Angiopoietin-2/Tie2 Complex Crystal Structure | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Barton, W.A, Nikolov, D.B. | 登録日 | 2006-05-09 | 公開日 | 2006-06-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex. Nat.Struct.Mol.Biol., 13, 2006
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3HPN
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![BU of 3hpn by Molmil](/molmil-images/mine/3hpn) | Ligand recognition by A-class EPH receptors: crystal structures of the EPHA2 ligand-binding domain and the EPHA2/EPHRIN-A1 complex | 分子名称: | Ephrin type-A receptor 2 | 著者 | Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B. | 登録日 | 2009-06-04 | 公開日 | 2009-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. Embo Rep., 10, 2009
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3HEI
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![BU of 3hei by Molmil](/molmil-images/mine/3hei) | Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex | 分子名称: | Ephrin type-A receptor 2, Ephrin-A1 | 著者 | Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B. | 登録日 | 2009-05-08 | 公開日 | 2009-06-30 | 最終更新日 | 2021-03-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. Embo Rep., 10, 2009
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1FVI
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![BU of 1fvi by Molmil](/molmil-images/mine/1fvi) | CRYSTAL STRUCTURE OF CHLORELLA VIRUS DNA LIGASE-ADENYLATE | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORELLA VIRUS DNA LIGASE-ADENYLATE, SULFATE ION | 著者 | Odell, M, Sriskanda, V, Shuman, S, Nikolov, D.B. | 登録日 | 2000-09-20 | 公開日 | 2000-11-22 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining. Mol.Cell, 6, 2000
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1IIM
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![BU of 1iim by Molmil](/molmil-images/mine/1iim) | thymidylyltransferase complexed with TTP | 分子名称: | THYMIDINE-5'-TRIPHOSPHATE, glucose-1-phosphate thymidylyltransferase | 著者 | Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B. | 登録日 | 2001-04-23 | 公開日 | 2001-05-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nat.Struct.Biol., 8, 2001
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1Z3S
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1KGY
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![BU of 1kgy by Molmil](/molmil-images/mine/1kgy) | Crystal Structure of the EphB2-ephrinB2 complex | 分子名称: | EPHRIN TYPE-B RECEPTOR 2, EPHRIN-B2 | 著者 | Himanen, J.P, Rajashankar, K.R, Lackmann, M, Cowan, C.A, Henkemeyer, M, Nikolov, D.B. | 登録日 | 2001-11-28 | 公開日 | 2002-05-28 | 最終更新日 | 2017-02-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of an Eph receptor-ephrin complex. Nature, 414, 2001
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1IIN
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![BU of 1iin by Molmil](/molmil-images/mine/1iin) | thymidylyltransferase complexed with UDP-glucose | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, glucose-1-phosphate thymidylyltransferase | 著者 | Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B. | 登録日 | 2001-04-23 | 公開日 | 2001-05-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nat.Struct.Biol., 8, 2001
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1Z3U
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6PD4
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![BU of 6pd4 by Molmil](/molmil-images/mine/6pd4) | Crystal Structure of Hendra Virus Attachment G Glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ... | 著者 | Xu, K, Nikolov, D.B. | 登録日 | 2019-06-18 | 公開日 | 2019-11-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2. PLoS ONE, 7, 2012
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6PDL
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3MX0
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![BU of 3mx0 by Molmil](/molmil-images/mine/3mx0) | Crystal Structure of EphA2 ectodomain in complex with ephrin-A5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ... | 著者 | Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S. | 登録日 | 2010-05-06 | 公開日 | 2010-06-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.506 Å) | 主引用文献 | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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3D11
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![BU of 3d11 by Molmil](/molmil-images/mine/3d11) | Crystal Structures of the Nipah G Attachment Glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase, ... | 著者 | Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B. | 登録日 | 2008-05-02 | 公開日 | 2008-08-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.306 Å) | 主引用文献 | Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc.Natl.Acad.Sci.USA, 105, 2008
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