1VOK
 
 | |
8GH4
 | | Complex of Adam 10 disentegrin cysteine rich domains with human monoclonal antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ... | | 著者 | Nikolov, D.B, Saha, N, Xu, K, Goldgur, Y. | | 登録日 | 2023-03-09 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells.
Biomed Pharmacother, 161, 2023
|
|
1VOL
 | | TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX | | 分子名称: | DNA (5'-D(*CP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ... | | 著者 | Nikolov, D.B, Chen, H, Halay, E.D, Usheva, A.U, Hisatake, K, Lee, D.K, Roeder, R.G, Burley, S.K. | | 登録日 | 1996-04-29 | | 公開日 | 1996-11-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of a TFIIB-TBP-TATA-element ternary complex.
Nature, 377, 1995
|
|
1CDW
 | | HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA | | 分子名称: | DNA (5'-D(*CP*AP*GP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)) | | 著者 | Nikolov, D.B, Chen, H, Halay, E.D, Hoffmann, A, Roeder, R.G, Burley, S.K. | | 登録日 | 1996-04-11 | | 公開日 | 1996-12-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a human TATA box-binding protein/TATA element complex.
Proc.Natl.Acad.Sci.USA, 93, 1996
|
|
7S7K
 | | Crystal structure of the EphB2 extracellular domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ... | | 著者 | Xu, Y, Xu, K, Nikolov, D.B. | | 登録日 | 2021-09-16 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism.
Int J Mol Sci, 22, 2021
|
|
1VTL
 | |
5EVM
 | |
5L0Q
 | | Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ... | | 著者 | Xu, K, Saha, N, Nikolov, D.B. | | 登録日 | 2016-07-28 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.759 Å) | | 主引用文献 | An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016
|
|
1MP5
 | | Y177F VARIANT OF S. ENTERICA RmlA | | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE | | 著者 | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | | 登録日 | 2002-09-11 | | 公開日 | 2002-10-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1MP4
 | | W224H VARIANT OF S. ENTERICA RmlA | | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, W224H Variant of S. Enterica RmlA Bound to UDP-Glucose | | 著者 | Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B. | | 登録日 | 2002-09-11 | | 公開日 | 2002-10-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
2AO7
 | | Adam10 Disintegrin and cysteine- rich domain | | 分子名称: | ADAM 10, SULFATE ION | | 著者 | Janes, P.W, Saha, N, Barton, W.A, Kolev, M.V, Wimmer-Kleikamp, S.H, Nievergall, E, Blobel, C.P, Himanen, J.-P, Lackmann, M, Nikolov, D.B. | | 登録日 | 2005-08-12 | | 公開日 | 2006-08-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
|
|
2GY5
 | | Tie2 Ligand-Binding Domain Crystal Structure | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ... | | 著者 | Barton, W.A, Nikolov, D.B. | | 登録日 | 2006-05-09 | | 公開日 | 2006-06-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
|
|
2GY7
 | | Angiopoietin-2/Tie2 Complex Crystal Structure | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Barton, W.A, Nikolov, D.B. | | 登録日 | 2006-05-09 | | 公開日 | 2006-06-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
|
|
3HPN
 | | Ligand recognition by A-class EPH receptors: crystal structures of the EPHA2 ligand-binding domain and the EPHA2/EPHRIN-A1 complex | | 分子名称: | Ephrin type-A receptor 2 | | 著者 | Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B. | | 登録日 | 2009-06-04 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
|
|
3HEI
 | | Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex | | 分子名称: | Ephrin type-A receptor 2, Ephrin-A1 | | 著者 | Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B. | | 登録日 | 2009-05-08 | | 公開日 | 2009-06-30 | | 最終更新日 | 2021-03-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
|
|
1FVI
 | | CRYSTAL STRUCTURE OF CHLORELLA VIRUS DNA LIGASE-ADENYLATE | | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORELLA VIRUS DNA LIGASE-ADENYLATE, SULFATE ION | | 著者 | Odell, M, Sriskanda, V, Shuman, S, Nikolov, D.B. | | 登録日 | 2000-09-20 | | 公開日 | 2000-11-22 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining.
Mol.Cell, 6, 2000
|
|
1IIM
 | | thymidylyltransferase complexed with TTP | | 分子名称: | THYMIDINE-5'-TRIPHOSPHATE, glucose-1-phosphate thymidylyltransferase | | 著者 | Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B. | | 登録日 | 2001-04-23 | | 公開日 | 2001-05-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
|
|
1Z3S
 | |
1KGY
 | | Crystal Structure of the EphB2-ephrinB2 complex | | 分子名称: | EPHRIN TYPE-B RECEPTOR 2, EPHRIN-B2 | | 著者 | Himanen, J.P, Rajashankar, K.R, Lackmann, M, Cowan, C.A, Henkemeyer, M, Nikolov, D.B. | | 登録日 | 2001-11-28 | | 公開日 | 2002-05-28 | | 最終更新日 | 2017-02-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of an Eph receptor-ephrin complex.
Nature, 414, 2001
|
|
1IIN
 | | thymidylyltransferase complexed with UDP-glucose | | 分子名称: | URIDINE-5'-DIPHOSPHATE-GLUCOSE, glucose-1-phosphate thymidylyltransferase | | 著者 | Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B. | | 登録日 | 2001-04-23 | | 公開日 | 2001-05-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
|
|
1Z3U
 | |
6PD4
 | | Crystal Structure of Hendra Virus Attachment G Glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ... | | 著者 | Xu, K, Nikolov, D.B. | | 登録日 | 2019-06-18 | | 公開日 | 2019-11-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2.
PLoS ONE, 7, 2012
|
|
6PDL
 | |
3MX0
 | | Crystal Structure of EphA2 ectodomain in complex with ephrin-A5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ... | | 著者 | Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S. | | 登録日 | 2010-05-06 | | 公開日 | 2010-06-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.506 Å) | | 主引用文献 | Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3D11
 | | Crystal Structures of the Nipah G Attachment Glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase, ... | | 著者 | Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B. | | 登録日 | 2008-05-02 | | 公開日 | 2008-08-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.306 Å) | | 主引用文献 | Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
