Tie2 Ligand-Binding Domain Crystal Structure

Summary for 2GY5

DescriptorAngiopoietin-1 receptor, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ... (4 entities in total)
Functional Keywordsligand-binding domain, transferase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein Q02763
Total number of polymer chains1
Total molecular weight48676.44
Barton, W.A.,Nikolov, D.B. (deposition date: 2006-05-09, release date: 2006-06-06, Last modification date: 2011-07-13)
Primary citation
Barton, W.A.,Tzvetkova-Robev, D.,Miranda, E.P.,Kolev, M.V.,Rajashankar, K.R.,Himanen, J.P.,Nikolov, D.B.
Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13:524-532, 2006
PubMed: 16732286 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1101
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.309193.8%7.1%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2gy5
no rotation
Molmil generated image of 2gy5
rotated about x axis by 90°
Molmil generated image of 2gy5
rotated about y axis by 90°